Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31462884 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL1893653 | 0.73 | HSD17B10 (0.41) | ALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL26273526 | 0.72 | MEN1 (0.36) | MAPT | |
| SCHEMBL3418047 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTCYP3A4HSD17B10 | |
| SCHEMBL29801033 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTCYP3A4HSD17B10 | |
| SCHEMBL27861303 | 0.71 | TNF (0.36) | ALDH1A1MAPTHPGDHSD17B10TNF | |
| SCHEMBL27717319 | 0.71 | PRCP (0.41) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL31462848 | 0.70 | CA12 (0.47) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL21203659 | 0.70 | CA12 (0.47) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL19810029 | 0.70 | ALDH1A1 (0.35) | ALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3577101-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-03-03 | — | — | EP | disclosed |
| WO-2018141706-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | WO | disclosed |