Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20468567 | 0.88 | TUBB4A (0.53) | MAOBMAOATUBB4ATUBBTUBA3C | |
| SCHEMBL20468566 | 0.84 | NQO2 (0.48) | MAOBMAOAPDE4BNPC1MAPT | |
| SCHEMBL5613888 | 0.80 | KDM4E (0.49) | PDE4BMAPTRECQLSMN1; SMN2HIF1A | |
| SCHEMBL5613889 | 0.80 | KDM4E (0.49) | PDE4BMAPTRECQLSMN1; SMN2HIF1A | |
| SCHEMBL1959689 | 0.79 | PDE4B (0.46) | PDE4BMAPTRECQLSMN1; SMN2HIF1A | |
| SCHEMBL1959686 | 0.79 | PDE4B (0.46) | PDE4BMAPTRECQLSMN1; SMN2HIF1A | |
| SCHEMBL4998760 | 0.78 | TUBB4A (0.51) | PDE4BMAPTRECQLSMN1; SMN2HIF1A | |
| SCHEMBL4998763 | 0.78 | TUBB4A (0.51) | PDE4BMAPTRECQLSMN1; SMN2HIF1A | |
| SCHEMBL1960200 | 0.77 | EGFR (0.54) | MAOBMAOANPC1MAPTRAB9A | |
| SCHEMBL1958432 | 0.77 | TUBB4A (0.46) | PDE4BMAPTRECQLSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144910-A1 | METHODS OF PROTECTING AGAINST NEURODEGENERATION | BIOVENTURES, LLC (US) | 2018-08-09 | — | — | WO | disclosed |