Icosapent

Icosapent

SCHEMBL20469

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 1.00
PPARG P37231 8/20 1.00
F7 P08709 7/20 1.00
F3 P13726 7/20 1.00
CYP19A1 P11511 6/20 1.00
PPARD Q03181 6/20 1.00
PPARA Q07869 6/20 1.00
PTGS1 P23219 5/20 1.00
OXER1 Q8TDS5 4/20 1.00
KMT2A Q03164 3/20 1.00
RXRA P19793 2/20 1.00
ADORA3 P0DMS8 1/20 1.00
FFAR1 O14842 5/20 0.85
MAPT P10636 4/20 0.85
L3MBTL1 Q9Y468 3/20 0.85
KDM4E B2RXH2 3/20 0.85
LMNA P02545 3/20 0.85
CYP3A4 P08684 3/20 0.85
HPGD P15428 3/20 0.85
ALOX15 P16050 3/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Icosapent SCHEMBL18185487 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL1648318 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
SCHEMBL12828369 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL1648015 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL2877007 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL2877002 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
SCHEMBL23417014 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL18185494 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL18274961 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL18185412 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 74106 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6361980-B1 None US claimed
US-20260146257-A1 METHOD FOR THE PRODUCTION OF HIGH LEVELS OF PUFA IN PLANTS BASF PLANT SCIENCE COMPANY GMBH (DE) 2026-05-28 US claimed
EP-4746844-A1 PERSONAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2026-05-27 EP claimed
EP-4746894-A1 NOVEL USE OF AN EXTRACT OF THE MICROALGA PHAEODACTYLUM TRICORNUTUM Microphyt (FR) 2026-05-27 EP claimed
US-12637408-B2 Lipid compositions comprising triacylglycerol with long-chain polyunsaturated fatty acids COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2026-05-26 US claimed
CN-122080243-A Saccharide supermolecule emulsifier and preparation method and application thereof 2026-05-26 CN claimed
US-12636281-B2 Dietary supplements to ameliorate dietary inadequacies related to brain health or neurodegenerative diseases, and methods to design dietary supplements NEURORESERVE INC. (US) 2026-05-26 US claimed
CN-122084801-A LC-MS/MS-based method for determining 11 polyunsaturated fatty acids 2026-05-26 CN claimed
CN-122095450-A Electrolytic capacitor 2026-05-26 CN claimed
US-12635714-B2 Compositions and methods for providing a health benefit to a growing animal Société des Produits Nestlé S.A. (CH) 2026-05-26 US claimed
EP-0222155-A1 5-Fluorouracil derivatives TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1987-05-20 EP claimed
EP-0085579-B1 TOPICAL PHARMACEUTICAL COMPOSITIONS EFAMOL LIMITED (GB) 1987-05-06 EP claimed
WO-1987002247-A1 RAPID ACTING INTRAVENOUS EMULSIONS OF OMEGA-3 FATTY ACID ESTERS BAXTER TRAVENOL LABORATORIES, INC. (US) 1987-04-23 WO claimed
US-4623488-A TRIGLYCERIDES HAVING HIGH CONTENT OF EICOSAPENTAENOIC ACID Q.P. CORPORATION (JP) 1986-11-18 US claimed
US-4615839-A EXTRACTION OF LIPIDS FROM CHLORELLA, DISTILLATION, HYDROLYSIS THE NISSHIN OIL MILLS, LTD. (JP) 1986-10-07 US claimed
US-4607052-A Triglycerides, dietetic and therapeutical applications and compositions containing them ROUSSEL-UCLAF (FR) 1986-08-19 US claimed
US-4513008-A Virucidal compositions and therapy THE VINOXEN COMPANY, INC. (US) 1985-04-23 US claimed
US-4438106-A STABILIZED ANTICHOLESTEROL AGENTS KUREHA KAGAKU KABUSHIKI KAISHA (JP) 1984-03-20 US claimed
EP-0085579-A2 Topical pharmaceutical compositions EFAMOL LIMITED (GB) 1983-08-10 EP claimed
US-4377526-A UREA, DISTILLATION NIPPON SUISAN KAISHA, LTD. (JP) 1983-03-22 US claimed