Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20468995 | 0.81 | — | — | |
| SCHEMBL20469165 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL14971531 | 0.78 | ERN1 (0.36) | ERN1 | |
| SCHEMBL20469090 | 0.75 | ERN1 (0.31) | ERN1 | |
| SCHEMBL24018468 | 0.71 | HPGD (0.34) | — | |
| SCHEMBL2981118 | 0.67 | ERN1 (0.54) | ERN1 | |
| SCHEMBL30423616 | 0.66 | HDAC6 (0.59) | — | |
| SCHEMBL25215904 | 0.66 | HDAC6 (0.59) | — | |
| SCHEMBL15652131 | 0.65 | ERN1 (0.55) | ERN1 | |
| SCHEMBL12703704 | 0.65 | ERN1 (0.42) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3909949-A1 | ATAZANAVIR (ATV) ANALOGUES FOR TREATING HIV INFECTIONS | Gilead Sciences, Inc. (US) | 2021-11-17 | — | — | EP | disclosed |
| EP-3577110-B1 | 8-OXETAN-3-YL-3,8-DIAZABICYCLO[3.2.1]OCTAN-3-YL SUBSTITUTED COMPOUNDS AS HIV INHIBITORS | GILEAD SCIENCES INC (US) | 2021-04-21 | — | — | EP | disclosed |
| WO-2018145021-A1 | ATAZANAVIR (ATV) ANALOGUES FOR TREATING HIV INFECTIONS | GILEAD SCIENCES, INC. (US) | 2018-08-09 | — | — | WO | disclosed |