SCHEMBL2047233

SCHEMBL2047233

Cc1ccccc1N=C=Nc1ccc(N=C=Nc2ccccc2C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
CYP3A4 P08684 3/20 0.47
TP53 P04637 1/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CYP2C9 P11712 1/20 0.39
TRPA1 O75762 1/20 0.39
ACHE P22303 1/20 0.39
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
MPI P34949 1/20 0.37
RECQL P46063 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SIGMAR1 Q99720 5/20 0.36
KMT2A Q03164 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL287022 0.94 TSHR (0.43) TSHRCYP3A4TP53MAPK1SMN1; SMN2
SCHEMBL508210 0.93 MIF (0.43) TSHRCYP3A4TP53MAPK1SMN1; SMN2
SCHEMBL8401752 0.93 MIF (0.43) TSHRCYP3A4TP53MAPK1SMN1; SMN2
SCHEMBL29516244 0.93 TSHR (0.47) TSHRCYP3A4TP53MAPK1SMN1; SMN2
SCHEMBL437747 0.93 TSHR (0.47) TSHRCYP3A4TP53MAPK1SMN1; SMN2
SCHEMBL9136636 0.82 TSHR (0.43) TSHRCYP3A4TP53MAPK1SMN1; SMN2
SCHEMBL28416749 0.81 TSHR (0.40) TSHRCYP3A4TP53MAPK1SMN1; SMN2
SCHEMBL28273815 0.80 TSHR (0.42) TSHRCYP3A4TP53MAPK1SMN1; SMN2
SCHEMBL18563044 0.79 CYP3A4 (0.56) TSHRCYP3A4TP53MAPK1SMN1; SMN2
SCHEMBL12589479 0.79 CYP3A4 (0.56) TSHRCYP3A4TP53MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134947-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER TECHNOLOGY CORPORATION 2018-05-17 US claimed
WO-2016159817-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER CANADA LIMITED (CA) 2016-10-06 WO claimed
US-11597833-B2 Thermoplastic resin composition for laser welding, molded article made of same, and composite molded article TORAY RESIN COMPANY (US) 2023-03-07 US disclosed
US-20220049086-A1 THERMOPLASTIC RESIN COMPOSITION FOR LASER WELDING, MOLDED ARTICLE MADE OF SAME, AND COMPOSITE MOLDED ARTICLE TORAY RESIN COMPANY (US) 2022-02-17 US disclosed
US-11161977-B2 Polycarbonate-based resin composition and molded product thereof IDEMITSU KOSAN CO., LTD. (JP) 2021-11-02 US disclosed
US-20210179776-A1 POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED PRODUCT THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2021-06-17 US disclosed
EP-3260501-B1 CURABLE RESIN COMPOSITION AND SEALING MATERIAL USING SAME NIPPON CATALYTIC CHEM IND (JP) 2021-01-27 EP disclosed
US-20200172703-A1 CURABLE RESIN COMPOSITION AND SEALING MATERIAL USING SAME NIPPON CATALYTIC CHEM IND (JP) 2020-06-04 US disclosed
US-10597517-B2 Curable resin composition and sealing material using same NIPPON SHOKUBAI CO., LTD. (JP) 2020-03-24 US disclosed
US-20190048184-A1 POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED PRODUCT THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2019-02-14 US disclosed
US-20180355113-A1 POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED ARTICLE THEREOF IDEMITSU KOSAN CO., LTD. (JP) 2018-12-13 US disclosed
EP-2351792-A1 POLYLACTIC ACID COMPOSITIONS AND MOLDED ARTICLES THEREOF Teijin Chemicals, Ltd. (JP) 2011-08-03 EP disclosed
EP-2330148-A1 POLYLACTIC ACID FILM Teijin Limited (JP) 2011-06-08 EP disclosed
US-20100324220-A1 RESIN COMPOSITION AND MOLDED ARTICLE TEIJIN LIMITED (JP) 2010-12-23 US disclosed
EP-2256165-A1 RESIN COMPOSITION AND MOLDED ARTICLE Teijin Limited (JP) 2010-12-01 EP disclosed
EP-2189493-A1 FILM Teijin Limited (JP) 2010-05-26 EP disclosed
US-20100004362-A1 POLYLACTIC ACID FIBER AND MANUFACTURING METHOD THEREOF( as amended TEIJIN LIMITED (JP) 2010-01-07 US disclosed
EP-2116576-A1 POLYLACTIC ACID COMPOSITION Teijin Limited (JP) 2009-11-11 EP disclosed
EP-2060665-A1 POLYLACTIC ACID FIBER AND METHOD FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 2009-05-20 EP disclosed
EP-2053091-A1 RESIN COMPOSITION, METHOD FOR PRODUCING THE SAME AND MOLDED ARTICLE TEIJIN LIMITED (JP) 2009-04-29 EP disclosed