SCHEMBL204726

SCHEMBL204726

O=C(O)Nc1nc2ccccc2[nH]1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 12/20 0.73
RAB9A P51151 11/20 0.73
SMN1; SMN2 Q16637 6/20 0.73
PKM P14618 5/20 0.73
MAOB P27338 1/20 0.73
ADORA2A P29274 1/20 0.73
LMNA P02545 3/20 0.73
CYP3A4 P08684 1/20 0.73
ALDH1A1 P00352 2/20 0.68
HSD17B10 Q99714 2/20 0.68
MAPK1 P28482 1/20 0.68
KLF5 Q13887 2/20 0.66
SCD O00767 1/20 0.66
OPRK1 P41145 1/20 0.66
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
TP53 P04637 3/20 0.62
ALOX12 P18054 1/20 0.62
GAA P10253 1/20 0.61
POLB P06746 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30416336 0.91 CYP3A4 (0.66) NPC1RAB9ASMN1; SMN2PKMMAOB
SCHEMBL5492024 0.89 LMNA (0.64) NPC1RAB9ASMN1; SMN2PKMMAOB
SCHEMBL23566380 0.87 NPC1 (0.75) NPC1RAB9ASMN1; SMN2PKMMAOB
SCHEMBL18106906 0.87 SMN1; SMN2 (0.63) NPC1RAB9ASMN1; SMN2PKMMAOB
SCHEMBL3926899 0.85 NPC1 (1.00) NPC1RAB9ASMN1; SMN2PKMMAOB
Benzimidazole SCHEMBL29406915 0.85 CYP3A4 (0.62) NPC1RAB9ASMN1; SMN2PKMMAOB
SCHEMBL12020635 0.84 LMNA (0.71) NPC1RAB9ASMN1; SMN2PKMMAOB
SCHEMBL29776932 0.84 CYP3A4 (1.00) NPC1RAB9ASMN1; SMN2PKMMAOB
SCHEMBL7788764 0.84 LMNA (0.71) NPC1RAB9ASMN1; SMN2PKMMAOB
SCHEMBL30968980 0.84 LMNA (1.00) NPC1RAB9ASMN1; SMN2PKMMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3907230-B1 NOVEL BENZIMIDAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE THEREOF AS ANTI-CANCER AGENT COMPRISING THE SAME BIOMETRIX TECH INC (KR) 2024-08-28 EP claimed
CN-118307992-A Environment-friendly primer for outer wall and preparation method and construction method thereof 苏州大乘环保新材有限公司 2024-07-09 CN claimed
WO-2023212494-A2 PREDICTIVE PESTICIDE RESISTANCE INFORMATION GENERATION AND USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-11-02 WO claimed
EP-4255175-A1 PREDICTIVE PESTICIDE RESISTANCE MAP GENERATION AND USE Pioneer Hi-Bred International, Inc. (US) 2023-10-11 EP claimed
US-20220264884-A1 SYNERGISTIC FUNGICIDE COMPOSITION UPL LTD (IN) 2022-08-25 US claimed
WO-2022099169-A1 PREDICTIVE PESTICIDE RESISTANCE MAP GENERATION AND USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2022-05-12 WO claimed
EP-3986133-A1 SYNERGISTIC FUNGICIDE COMPOSITION UPL Limited (IN) 2022-04-27 EP claimed
CN-112280428-A Preparation process of water-based paint 陈雪炎 2021-01-29 CN claimed
WO-2020261030-A1 SYNERGISTIC FUNGICIDE COMPOSITION UPL LIMITED (IN) 2020-12-30 WO claimed
US-20200221703-A1 BACTERIAL STRAINS AND THEIR USE FOR CONTROLLING PLANT DISEASE AgBiome, Inc. (US) 2020-07-16 US claimed
EP-0008047-B1 5(6)-(2-AMINO-5-THIAZOLOYL)BENZIMIDAZOLE-2-CARBAMIC ACID ESTERS AND THEIR SALTS, THEIR PREPARATION AND USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1985-12-04 EP claimed
EP-0063905-B1 FUNGICIDAL N-PHENYLCARBAMATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-08-14 EP claimed
EP-0078663-B1 FUNGICIDAL N-PHENYLCARBAMATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-04-17 EP claimed
EP-0014443-B1 DILUTABLE ALKYL-BENZIMIDAZOLECARBAMATE FORMULATION, PROCESS FOR ITS PREPARATION AND ITS USE AS BIOCIDE RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1982-11-03 EP claimed
US-4299837-A IN ANIMALS MONTEDISON S.P.A. (IT) 1981-11-10 US claimed
EP-0008047-A1 5(6)-(2-Amino-5-thiazoloyl)benzimidazole-2-carbamic acid esters and their salts, their preparation and use, and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1980-02-20 EP claimed
EP-0003951-A1 Process for the preparation of 2-benzimidazolecarbamic acid esters ETHYL CORPORATION (US) 1979-09-19 EP claimed
US-4152522-A FROM ORTHO-NITROANILINE ETHYL CORPORATION (US) 1979-05-01 US claimed
US-4053598-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-11 US claimed
US-4032536-A ANTHELMINTICS JANSSEN PHARMACEUTICA N.V. (BE) 1977-06-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220264884-A1 SYNERGISTIC FUNGICIDE COMPOSITION MANBA, MAN2A1, MAN2B1 NPC1 2802/4885RAB9A 1247/4885SMN1; SMN2 2652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.