Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL8421397 | 1.00 | TP53 (0.47) | TP53OR51E2GABRR1SLC7A5RNPEP | |
| Ethylene Glycol SCHEMBL2948674 | 1.00 | TP53 (0.47) | TP53OR51E2GABRR1SLC7A5RNPEP | |
| 1,4-Butanediol SCHEMBL28822648 | 0.87 | GPR84 (0.46) | TP53OR51E2RNPEPCYP1A2CHRM1 | |
| 1,3-Propanediol SCHEMBL28283379 | 0.87 | CAMK2A (0.43) | TP53OR51E2GABRR1SLC7A5RNPEP | |
| Alcohol SCHEMBL6527782 | 0.86 | — | — | |
| SCHEMBL405938 | 0.84 | TP53 (0.61) | TP53SLC7A5RNPEPCYP1A2TDP1 | |
| SCHEMBL2531259 | 0.84 | TP53 (0.61) | TP53SLC7A5RNPEPCYP1A2TDP1 | |
| SCHEMBL5940223 | 0.84 | TP53 (0.61) | TP53SLC7A5RNPEPCYP1A2TDP1 | |
| SCHEMBL17767389 | 0.84 | TP53 (0.61) | TP53SLC7A5RNPEPCYP1A2TDP1 | |
| SCHEMBL2774033 | 0.84 | TP53 (0.61) | TP53SLC7A5RNPEPCYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11672776-B2 | Multi-arm polymeric alkanoate conjugates | NEKTAR THERAPEUTICS (US) | 2023-06-13 | — | — | US | disclosed |
| US-20190029991-A1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | NEKTAR THERAPEUTICS | 2019-01-31 | — | — | US | disclosed |
| US-10039737-B2 | Multi-arm polymeric alkanoate conjugates | NEKTAR THERAPEUTICS (US) | 2018-08-07 | — | — | US | disclosed |
| EP-2331140-B1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | NEKTAR THERAPEUTICS (US) | 2018-07-04 | — | — | EP | disclosed |
| US-20170189369-A1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | NEKTAR THERAPEUTICS | 2017-07-06 | — | — | US | disclosed |
| US-9504755-B2 | Multi-arm polymeric alkanoate conjugates | NEKTAR THERAPEUTICS (US) | 2016-11-29 | — | — | US | disclosed |
| US-8637466-B2 | Multi-arm polymeric alkanoate conjugates | NEKTAR THERAPEUTICS (US) | 2014-01-28 | — | — | US | disclosed |
| US-20110200550-A1 | Multi-Arm Polymeric Alkanoate Conjugates | NEKTAR THERAPEUTICS (US) | 2011-08-18 | — | — | US | disclosed |
| EP-2331140-A1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | Nektar Therapeutics (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010019233-A1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | NEKTAR THERAPEUTICS (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189369-A1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | ALK, ALKBH3, PAICS | TP53 2298/4885OR51E2 2673/4885GABRR1 946/4885 |
| US-20110200550-A1 | Multi-Arm Polymeric Alkanoate Conjugates | ALK, ALKBH3, PAICS | TP53 2298/4885OR51E2 2673/4885GABRR1 946/4885 |
| US-11672776-B2 | Multi-arm polymeric alkanoate conjugates | ALK, ALKBH3, PAICS | TP53 2298/4885OR51E2 2673/4885GABRR1 946/4885 |
| US-20190029991-A1 | MULTI-ARM POLYMERIC ALKANOATE CONJUGATES | ALK, ALKBH3, PAICS | TP53 2298/4885OR51E2 2673/4885GABRR1 946/4885 |
| US-10039737-B2 | Multi-arm polymeric alkanoate conjugates | ALK, ALKBH3, PAICS | TP53 2298/4885OR51E2 2673/4885GABRR1 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.