⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16062057 | 1.00 | — | — | |
| SCHEMBL9185446 | 0.92 | — | — | |
| SCHEMBL9187254 | 0.90 | GPR84 (0.54) | — | |
| SCHEMBL9180827 | 0.90 | GPR84 (0.54) | — | |
| SCHEMBL9185247 | 0.90 | GPR84 (0.54) | — | |
| SCHEMBL9184839 | 0.90 | GPR84 (0.54) | — | |
| SCHEMBL5183196 | 0.90 | GPR84 (0.54) | — | |
| SCHEMBL9181739 | 0.90 | GPR84 (0.54) | — | |
| SCHEMBL9186713 | 0.90 | GPR84 (0.54) | — | |
| SCHEMBL11761608 | 0.90 | GPR84 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4236201-A | — | — | None | — | — | JP | disclosed |
| US-7956041-B2 | antidiabetic mixture contains an inhibitor of renal glucose reabsorption and a hypoglycemic agent; controlling blood glucose level; tolbutamide, chlorpropamide, glibenclamide, glipizide, glimepiride, and gliclazide; metformin, phenformin and buformin; repaglinide, nateglinide and mitiglinide | AJINOMOTO CO., INC. (JP) | 2011-06-07 | — | — | US | disclosed |
| US-7465712-B2 | Glucopyranosyloxy benzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-12-16 | — | — | US | disclosed |
| US-7129381-B2 | Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-10-31 | — | — | US | disclosed |
| US-7053060-B2 | Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-30 | — | — | US | disclosed |
| US-7045665-B2 | Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-05-16 | — | — | US | disclosed |
| EP-1270584-B1 | GLUCOPYRANOSYLOXY BENZYLBENZENE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES FOR THE PREPARATION OF THE DERIVATIVES | KISSEI PHARMACEUTICAL (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-20050143424-A1 | Prophylactic and therapeutic agent of diabetes mellitus | AJINOMOTO CO. INC (JP) | 2005-06-30 | — | — | US | disclosed |
| US-20050113315-A1 | Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates in the production thereof | KISSEI PHARMACEUTICAL CO., LTD. | 2005-05-26 | — | — | US | disclosed |
| US-20050080022-A1 | Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives | KISSEI PHARMACEUTICAL CO., LTD. | 2005-04-14 | — | — | US | disclosed |
| US-4729839-A | THIO ESTER-ETHERS, ESTERIFICATION, ETHERIFICATION | PHILLIPS PETROLEUM COMPANY (US) | 1988-03-08 | — | — | US | disclosed |
| EP-0249783-A1 | Water soluble lubricating additives | PHILLIPS PETROLEUM COMPANY (US) | 1987-12-23 | — | — | EP | disclosed |
| US-4643823-A | FROTH FLOTATION | PHILLIPS PETROLEUM COMPANY (US) | 1987-02-17 | — | — | US | disclosed |
| US-4636487-A | Process for the preparation of promoted catalysts | PHILLIPS PETROLEUM COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| EP-0200212-A2 | Process for producing polythiobisphenols and process for producing mercaptophenols by the hydrogenolysis of the same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1986-11-05 | — | — | EP | disclosed |
| US-4607049-A | A(TICOAGULANTS AND BRONCHODILATOR AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| US-4582594-A | MERCAPTO ALCOHOL AND MOLYBDENUM COMPOUND REACTION PRODUCT ACTIVATING HYDROREFINING CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1986-04-15 | — | — | US | disclosed |
| US-RE29243-E | HAS SURFACE-ACTIVE PROPERTIES | HENKEL & CIE G.M.B.H. (DT) | 1977-05-31 | — | — | US | disclosed |
| US-4001310-A | POLYETHERS HAVING OXIDIZED THIOETHER SIDE CHAINS | THE DOW CHEMICAL COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3932487-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-13 | — | — | US | disclosed |