SCHEMBL20473603

SCHEMBL20473603

NC(=O)c1cc(F)c(NC2CCCCC2N)nc1Nc1ccnc2c1ccn2CC(=O)N1CCOCC1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SYK P43405 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14929903 1.00 SYK (0.48) SYK
SCHEMBL14931155 1.00 SYK (0.48) SYK
SCHEMBL14929896 0.94 SYK (0.49) SYK
SCHEMBL14923825 0.94 SYK (0.49) SYK
SCHEMBL14911474 0.90 SYK (0.49) SYK
SCHEMBL14908918 0.90 SYK (0.49) SYK
SCHEMBL14909804 0.89 SYK (0.52) SYK
SCHEMBL20473636 0.89 SYK (0.52) SYK
SCHEMBL14911256 0.87 SYK (0.50) SYK
SCHEMBL14929905 0.87 SYK (0.51) SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2589592-B1 NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF FUJIFILM CORP (JP) 2018-08-22 — — EP disclosed
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