Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537437 | 0.85 | JAK3 (1.00) | JAK3 | |
| SCHEMBL1992632 | 0.85 | JAK3 (1.00) | JAK3 | |
| SCHEMBL28051524 | 0.85 | JAK3 (0.69) | JAK3 | |
| SCHEMBL1993327 | 0.84 | JAK3 (0.77) | JAK3 | |
| Hydrochloric Acid SCHEMBL1991208 | 0.84 | JAK3 (0.97) | JAK3 | |
| Hydrochloric Acid SCHEMBL2022955 | 0.84 | JAK3 (0.68) | JAK3 | |
| SCHEMBL30520105 | 0.83 | JAK3 (0.76) | JAK3 | |
| SCHEMBL13505339 | 0.83 | JAK3 (0.76) | JAK3 | |
| Hydrochloric Acid SCHEMBL1995265 | 0.83 | JAK3 (0.76) | JAK3 | |
| SCHEMBL19085143 | 0.83 | POLB (0.59) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516392-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011076678-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-06-30 | — | — | WO | disclosed |