Phenazine

Phenazine

SCHEMBL20475337

[Fe].c1ccc2nc3ccccc3nc2c1

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.92
NQO2 P16083 6/20 0.65
ALDH1A1 P00352 7/20 0.59
HPGD P15428 4/20 0.59
KDM4E B2RXH2 4/20 0.59
HSD17B10 Q99714 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
GLA P06280 2/20 0.59
ACHE P22303 2/20 0.59
GAA P10253 2/20 0.59
KMT2A Q03164 4/20 0.58
MEN1 O00255 3/20 0.58
POLB P06746 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
NPC1 O15118 2/20 0.58
USP2 O75604 1/20 0.58
CACNA1B Q00975 1/20 0.58
APBA1 Q02410 1/20 0.58
RAB9A P51151 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenazine SCHEMBL27643128 0.96 MAPT (1.00) MAPTNQO2ALDH1A1HPGDKDM4E
Phenazine SCHEMBL29356959 0.96 MAPT (1.00) MAPTNQO2ALDH1A1HPGDKDM4E
Phenazine SCHEMBL9049 0.96 MAPT (1.00) MAPTNQO2ALDH1A1HPGDKDM4E
Phenazine SCHEMBL11126178 0.92 MAPT (0.92) MAPTNQO2ALDH1A1HPGDKDM4E
Phenazine SCHEMBL10866237 0.92 MAPT (0.92) MAPTNQO2ALDH1A1HPGDKDM4E
Phenazine SCHEMBL6329249 0.92 MAPT (0.92) MAPTNQO2ALDH1A1HPGDKDM4E
Phenazine SCHEMBL20475326 0.92 MAPT (0.92) MAPTNQO2ALDH1A1HPGDKDM4E
Phenazine SCHEMBL22345160 0.92 MAPT (0.92) MAPTNQO2ALDH1A1HPGDKDM4E
Phenazine SCHEMBL17187692 0.92 MAPT (0.92) MAPTNQO2ALDH1A1HPGDKDM4E
Phenazine SCHEMBL3119916 0.92 MAPT (0.92) MAPTNQO2ALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11053205-B2 Phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2021-07-06 US disclosed
WO-2018152436-A1 PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS UNIVERSITY OF RESEARCH FOUNDATION, INCORPORATED (US) 2018-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11053205-B2 Phenazine derivatives as antimicrobial agents ROS1, NOX4, PRDX3 MAPT 2601/4885NQO2 172/4885ALDH1A1 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.