Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.45 |
| ▸ | TXN | P10599 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22926257 | 0.85 | NPSR1 (0.54) | NPSR1CYP1A2CYP2C9DDAH1TXN | |
| SCHEMBL14361622 | 0.83 | NPSR1 (0.51) | NPSR1CYP1A2CYP2C9DDAH1TXN | |
| SCHEMBL13073559 | 0.81 | NPSR1 (0.58) | NPSR1CYP1A2DDAH1TXNKDM4E | |
| SCHEMBL14361831 | 0.80 | NPSR1 (0.49) | NPSR1CYP1A2DDAH1KDM4EALDH1A1 | |
| SCHEMBL22016725 | 0.80 | NPSR1 (0.56) | NPSR1CYP1A2CYP2C9DDAH1TXN | |
| SCHEMBL229852 | 0.79 | NPSR1 (0.68) | NPSR1CYP1A2DDAH1TXNKDM4E | |
| SCHEMBL38661952 | 0.78 | NPSR1 (0.61) | NPSR1DDAH1TXNKDM4EALDH1A1 | |
| SCHEMBL15294544 | 0.78 | NPSR1 (0.61) | NPSR1CYP1A2CYP2C9DDAH1TXN | |
| SCHEMBL846351 | 0.77 | NPSR1 (0.66) | NPSR1DDAH1TXNKDM4EALDH1A1 | |
| SCHEMBL30633367 | 0.77 | NPSR1 (0.66) | NPSR1DDAH1TXNKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11130750-B2 | Calcium channel inhibitors | CAVION, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-11130750-B2 | Calcium channel inhibitors | CAVION, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200385367-A1 | CALCIUM CHANNEL INHIBITORS | CAVION, INC. | 2020-12-10 | — | — | US | disclosed |
| US-20200385367-A1 | CALCIUM CHANNEL INHIBITORS | CAVION, INC. | 2020-12-10 | — | — | US | disclosed |
| CN-110545806-A | calcium channel inhibitors | CAVION INC | 2019-12-06 | — | — | CN | disclosed |
| WO-2018152317-A1 | CALCIUM CHANNEL INHIBITORS | CAVION, INC. (US) | 2018-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130750-B2 | Calcium channel inhibitors | CACNA1F, ORAI1, CACNA1E | NPSR1 2663/4885CYP1A2 4490/4885CYP2C9 3409/4885 |
| US-20200385367-A1 | CALCIUM CHANNEL INHIBITORS | CACNA1F, ORAI1, CACNA1E | NPSR1 2663/4885CYP1A2 4490/4885CYP2C9 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.