Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | TXN | P10599 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073559 | 0.84 | NPSR1 (0.58) | NPSR1DDAH1TXNALDH1A1KDM4E | |
| SCHEMBL22926257 | 0.81 | NPSR1 (0.54) | NPSR1DDAH1TXNALDH1A1KDM4E | |
| SCHEMBL229852 | 0.81 | NPSR1 (0.68) | NPSR1DDAH1TXNALDH1A1KDM4E | |
| SCHEMBL20476291 | 0.80 | NPSR1 (0.53) | NPSR1DDAH1TXNALDH1A1KDM4E | |
| SCHEMBL846351 | 0.80 | NPSR1 (0.66) | NPSR1DDAH1TXNALDH1A1KDM4E | |
| SCHEMBL30633367 | 0.80 | NPSR1 (0.66) | NPSR1DDAH1TXNALDH1A1KDM4E | |
| SCHEMBL22734741 | 0.79 | NPSR1 (0.51) | NPSR1DDAH1TXNALDH1A1KDM4E | |
| SCHEMBL14361622 | 0.79 | NPSR1 (0.51) | NPSR1DDAH1TXNALDH1A1KDM4E | |
| SCHEMBL22017306 | 0.78 | NPSR1 (0.44) | NPSR1DDAH1ALDH1A1NPC1RAB9A | |
| SCHEMBL22017033 | 0.78 | NPSR1 (0.50) | NPSR1DDAH1TXNALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981899-B2 | Inhibitors of soluble adenylyl cyclase | CORNELL UNIVERSITY (US) | 2021-04-20 | — | — | US | disclosed |
| US-20200157084-A1 | INHIBITORS OF SOLUBLE ADENYLYL CYCLASE | TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981899-B2 | Inhibitors of soluble adenylyl cyclase | PDE7A, PDE6C, ADCYAP1R1 | NPSR1 3082/4885DDAH1 891/4885TXN 3510/4885 |
| US-20200157084-A1 | INHIBITORS OF SOLUBLE ADENYLYL CYCLASE | PDE7A, PDE6C, PDE8B | NPSR1 3616/4885DDAH1 831/4885TXN 3521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.