Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20476345 | 0.81 | ALDH1A1 (0.53) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL7833255 | 0.81 | NOTUM (0.65) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL18763042 | 0.79 | SLC22A12 (0.58) | CASP3CASP2MAPTALDH1A1MEN1 | |
| SCHEMBL28204772 | 0.78 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9181801 | 0.77 | KDM4E (0.57) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL12194132 | 0.76 | HPGD (0.64) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL1928973 | 0.75 | TSHR (0.75) | CASP3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29770335 | 0.75 | TSHR (0.75) | CASP3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6646056 | 0.75 | DRD4 (0.64) | CASP3CASP2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14058976 | 0.75 | CA1 (0.64) | CASP3CASP2MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018150347-A1 | COMPOUNDS WITH BETA-ADRENERGIC AGONIST AND ANTIMUSCARINIC ACTIVITY | TORRENT PHARMACEUTICALS LIMITED (IN) | 2018-08-23 | — | — | WO | disclosed |