Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670769 | 0.83 | ALDH1A1 (0.37) | TDP1ALDH1A1MAPK1CYP3A4CA2 | |
| SCHEMBL5873246 | 0.82 | TDP1 (0.38) | TDP1ALDH1A1MAPK1CYP3A4CA2 | |
| SCHEMBL4551543 | 0.79 | TDP1 (0.35) | TDP1ALDH1A1MAPK1CYP3A4CA2 | |
| SCHEMBL8589000 | 0.76 | TDP1 (0.37) | TDP1ALDH1A1MAPK1CYP3A4CA2 | |
| SCHEMBL659128 | 0.75 | ALDH1A1 (0.44) | TDP1ALDH1A1MAPK1CYP3A4CA2 | |
| SCHEMBL594300 | 0.73 | ALDH1A1 (0.37) | TDP1ALDH1A1MAPK1CYP3A4CA2 | |
| SCHEMBL3094200 | 0.71 | ALDH1A1 (0.35) | TDP1ALDH1A1MAPK1CYP3A4CA2 | |
| SCHEMBL22499622 | 0.71 | TDP1 (0.46) | TDP1ALDH1A1MAPK1CYP3A4CA2 | |
| SCHEMBL17138127 | 0.71 | CYP3A4 (0.49) | TDP1ALDH1A1MAPK1CYP3A4CA2 | |
| SCHEMBL1357035 | 0.70 | ALDH1A1 (0.50) | TDP1ALDH1A1MAPK1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431434-B2 | Derivatized fullerene-based dopants for organic semiconductors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2013-04-30 | — | — | US | disclosed |
| US-20110156019-A1 | DERIVATIZED FULLERENE-BASED DOPANTS FOR ORGANIC SEMICONDUCTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION, LTD. (IL) | 2011-06-30 | — | — | US | disclosed |