Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17978906 | 0.80 | HRH3 (0.40) | TSHRSCN9AGPR183KCNH2KDM4E | |
| SCHEMBL29516737 | 0.69 | PIM1 (0.42) | ALDH1A1AKR1C3 | |
| SCHEMBL23293623 | 0.67 | EP300 (0.37) | TSHRKDM4EALDH1A1DGAT1HRH3 | |
| SCHEMBL30117294 | 0.67 | CYP4F2 (0.43) | TSHRSCN9AGPR183KCNH2KDM4E | |
| SCHEMBL30117296 | 0.67 | CYP4F2 (0.43) | TSHRSCN9AGPR183KCNH2KDM4E | |
| SCHEMBL486202 | 0.66 | ALDH1A1 (0.52) | TSHRKDM4EALDH1A1DGAT1 | |
| SCHEMBL2414089 | 0.65 | KDM4E (0.46) | TSHRGPR183KDM4EALDH1A1DGAT1 | |
| SCHEMBL2899777 | 0.65 | KDM4E (0.46) | TSHRKDM4EALDH1A1DGAT1 | |
| SCHEMBL25315094 | 0.64 | HRH3 (0.40) | SCN9AKCNH2ALDH1A1HRH3 | |
| SCHEMBL26633220 | 0.64 | SCN9A (0.52) | SCN9AKCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018149226-A1 | AMINO PYRIMIDINE COMPOUNDS USEFUL AS SSAO INHIBITORS | ELI LILLY AND COMPANY (US) | 2018-08-23 | — | — | WO | disclosed |