Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17140903 | 1.00 | KDM4E (0.37) | KDM4ETSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL17140900 | 0.92 | KDM4E (0.41) | KDM4ETSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL17140897 | 0.92 | KDM4E (0.41) | KDM4ETSHRALDH1A1HSD17B10ALOX15 | |
| Hydrochloric Acid SCHEMBL7407411 | 0.83 | ELANE (0.37) | ALDH1A1MEN1KMT2ATDP1BTK | |
| SCHEMBL17150685 | 0.80 | MEN1 (0.39) | KDM4ETSHRALDH1A1MEN1KMT2A | |
| SCHEMBL19533587 | 0.79 | TSHR (0.49) | KDM4ETSHRALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15584092 | 0.78 | SMN1; SMN2 (0.46) | KDM4ETSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL16444453 | 0.78 | SMN1; SMN2 (0.46) | KDM4ETSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL17250749 | 0.77 | KDM4E (0.40) | KDM4ETSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL14165795 | 0.76 | KDM4E (0.42) | KDM4ETSHRALDH1A1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10059690-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2018-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10059690-B2 | Inhibitors of cyclin-dependent kinase 7 (CDK7) | CDK7, CDK3, CDK9 | KDM4E 1501/4885TSHR 3200/4885ALDH1A1 3898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.