Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 8/20 | 0.60 |
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14673291 | 1.00 | CAPN1 (0.60) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL14673292 | 1.00 | CAPN1 (0.60) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL14682289 | 0.92 | CAPN1 (0.55) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL14728337 | 0.92 | CAPN1 (0.55) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL15576934 | 0.92 | CAPN1 (0.55) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL19492652 | 0.89 | CAPN1 (0.62) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL28633182 | 0.88 | CAPN1 (0.50) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL28644179 | 0.88 | CAPN1 (0.50) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL16488741 | 0.87 | CAPN1 (0.62) | CAPN1CTSBOPRM1 | |
| SCHEMBL17229184 | 0.87 | CAPN1 (0.62) | CAPN1CTSBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771021-B1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | NORTH WESTERN UNIV (US) | 2018-08-29 | — | — | EP | disclosed |