Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15576934 | 1.00 | CAPN1 (0.55) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL14673291 | 0.92 | CAPN1 (0.60) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL14673292 | 0.92 | CAPN1 (0.60) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL20477645 | 0.92 | CAPN1 (0.60) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL14682289 | 0.89 | CAPN1 (0.55) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL14728349 | 0.88 | CAPN1 (0.57) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL20993822 | 0.87 | CAPN1 (0.53) | CAPN1CTSBOPRM1 | |
| SCHEMBL14728356 | 0.86 | CAPN1 (0.58) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL16994620 | 0.86 | CAPN1 (0.58) | CAPN1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL14673120 | 0.84 | CAPN1 (0.65) | CAPN1CTSBOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593145-B2 | Secondary structure stabilized NMDA receptor modulators and uses thereof | NORTHWESTERN UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160115197-A1 | SECONDARY STRUCTURE STABILIZED NMDA RECEPTOR MODULATORS AND USES THEREOF | INNOVIVA TRC HOLDINGS LLC | 2016-04-28 | — | — | US | disclosed |
| US-9101612-B2 | Secondary structure stabilized NMDA receptor modulators and uses thereof | NORTHWESTERN UNIVERSITY (US) | 2015-08-11 | — | — | US | disclosed |
| US-20130053325-A1 | Secondary Structure Stabilized NMDA Receptor Modulators and Uses Thereof | INNOVIVA TRC HOLDINGS LLC | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053325-A1 | Secondary Structure Stabilized NMDA Receptor Modulators and Uses Thereof | GRIN2A, GRIN1, GRIN3A | CAPN1 1536/4885CTSB 4297/4885OPRM1 27/4885 |
| US-20160115197-A1 | SECONDARY STRUCTURE STABILIZED NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN2A, GRIN1, GRIN3A | CAPN1 1536/4885CTSB 4297/4885OPRM1 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.