Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.71 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.67 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.67 |
| ▸ | VDR | P11473 | 4/20 | 0.66 |
| ▸ | CASP7 | P55210 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.66 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | MDM4 | O15151 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20480609 | 1.00 | ST6GAL1 (0.71) | ST6GAL1GRIN1GRIN2BVDRCASP7 | |
| SCHEMBL20480607 | 1.00 | ST6GAL1 (0.71) | ST6GAL1GRIN1GRIN2BVDRCASP7 | |
| SCHEMBL18576208 | 1.00 | ST6GAL1 (0.71) | ST6GAL1GRIN1GRIN2BVDRCASP7 | |
| SCHEMBL18575958 | 0.92 | VDR (0.69) | ST6GAL1GRIN1GRIN2BVDRCASP7 | |
| SCHEMBL18575957 | 0.92 | VDR (0.69) | ST6GAL1GRIN1GRIN2BVDRCASP7 | |
| SCHEMBL22855507 | 0.89 | ST6GAL1 (0.65) | ST6GAL1VDRCASP7HSD17B10GPBAR1 | |
| SCHEMBL22855309 | 0.87 | VDR (0.73) | VDRCASP7HSD17B10GPBAR1TDP1 | |
| SCHEMBL22855506 | 0.87 | EPHA2 (0.65) | ST6GAL1VDRCASP7HSD17B10GPBAR1 | |
| SCHEMBL22855508 | 0.87 | EPHA2 (0.65) | ST6GAL1VDRCASP7HSD17B10GPBAR1 | |
| SCHEMBL22855456 | 0.85 | VDR (0.70) | VDRCASP7HSD17B10GPBAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ACADEMIA SINICA (TW) | 2021-01-12 | — | — | US | disclosed |
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ACADEMIA SINICA (TW) | 2021-01-12 | — | — | US | disclosed |
| US-20180244713-A1 | SIALYLTRANSFERASE INHIBITORS AND USES THEREOF | ACADEMIA SINICA (TW) | 2018-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10889611-B2 | Sialyltransferase inhibitors and uses thereof | ST6GAL1, NEU1, GALNT1 | ST6GAL1 1/4885GRIN1 4370/4885GRIN2B 4554/4885 |
| US-20180244713-A1 | SIALYLTRANSFERASE INHIBITORS AND USES THEREOF | ST6GAL1, NEU1, GALNT1 | ST6GAL1 1/4885GRIN1 4370/4885GRIN2B 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.