Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 7/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7921140 | 0.76 | CREBBP (0.37) | ALDH1A1KDM4ESMN1; SMN2GAAOGA | |
| SCHEMBL30876831 | 0.75 | NPC1 (0.35) | ALDH1A1KDM4ESMN1; SMN2OGATDP1 | |
| SCHEMBL23314225 | 0.74 | OGA (0.35) | ALDH1A1KDM4EOGAGLATDP1 | |
| SCHEMBL25054104 | 0.72 | OGA (0.34) | OGATDP1PBRM1 | |
| SCHEMBL20482093 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2GAAOGA | |
| SCHEMBL23314238 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2GAAOGA | |
| SCHEMBL20482091 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2GAAOGA | |
| SCHEMBL23282497 | 0.70 | OGA (0.46) | OGATDP1BRD4CREBBP | |
| SCHEMBL23314228 | 0.70 | OGA (0.43) | OGABRD4CREBBP | |
| SCHEMBL21753262 | 0.68 | ALDH1A1 (0.38) | ALDH1A1TDP1HSD17B10DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10995090-B2 | Substituted dihydrobenzofuran glycosidase inhibitors | ASCENEURON SA (CH) | 2021-05-04 | — | — | US | disclosed |
| US-10995090-B2 | Substituted dihydrobenzofuran glycosidase inhibitors | ASCENEURON SA (CH) | 2021-05-04 | — | — | US | disclosed |
| WO-2018153507-A1 | SUBSTITUTED DIHYDROBENZOFURAN GLYCOSIDASE INHIBITORS | Asceneuron S.A. (CH) | 2018-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10995090-B2 | Substituted dihydrobenzofuran glycosidase inhibitors | GAA, ENGASE, BACE1 | ALDH1A1 403/4885KDM4E 1527/4885SMN1; SMN2 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.