Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050067 | 0.95 | MAPT (0.48) | MAPTLMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL2048393 | 0.79 | MAPT (0.46) | MAPTLMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL2045340 | 0.76 | HTR1B (0.48) | MAPTLMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL2050062 | 0.76 | MAPT (0.47) | MAPTLMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL2018028 | 0.74 | KMT2A (0.45) | MAPTLMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL3687749 | 0.70 | MAPT (0.63) | MAPTLMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL6447738 | 0.70 | F2 (0.74) | MAPTLMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL29643283 | 0.70 | F2 (0.74) | MAPTLMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL2048468 | 0.70 | HTR1B (0.47) | MAPTLMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL3687747 | 0.68 | MAPKAPK2 (0.52) | MAPTSMN1; SMN2MEN1KMT2AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160180-A1 | Cannabinoid Receptor Ligands | ASTRAZENECA AB (SE) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160180-A1 | Cannabinoid Receptor Ligands | CNR1, CNR2, OPRL1 | MAPT 3104/4885LMNA 3820/4885ALDH1A1 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.