SCHEMBL20484121

SCHEMBL20484121

CC(C)CC(NC(=O)Nc1ccc(Br)cc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 15/20 1.00
ALDH1A1 P00352 1/20 0.67
LMNA P02545 1/20 0.67
MAPT P10636 1/20 0.66
RAB9A P51151 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14889800 1.00 FPR2 (1.00) FPR2ALDH1A1LMNAMAPTRAB9A
SCHEMBL14903135 1.00 FPR2 (1.00) FPR2ALDH1A1LMNAMAPTRAB9A
SCHEMBL14902570 0.90 FPR2 (0.81) FPR2ALDH1A1LMNAMAPT
SCHEMBL16008319 0.88 FPR2 (0.79) FPR2RAB9A
SCHEMBL14889619 0.88 FPR2 (0.78) FPR2
SCHEMBL19723124 0.88 FPR2 (0.78) FPR2
SCHEMBL16008318 0.87 FPR2 (0.77) FPR2RAB9A
SCHEMBL14902804 0.87 FPR2 (0.77) FPR2ALDH1A1LMNARAB9A
SCHEMBL22175170 0.87 FPR2 (0.77) FPR2ALDH1A1LMNARAB9A
SCHEMBL18083036 0.87 FPR2 (0.77) FPR2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3795148-B1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN INC (US) 2025-06-18 EP disclosed
EP-3795148-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2021-03-24 EP disclosed
EP-3078656-B1 AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2020-07-01 EP disclosed
EP-3078656-B1 AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2020-07-01 EP disclosed
EP-2770989-B1 AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS ALLERGAN INC (US) 2018-09-05 EP disclosed