Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 18/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14902611 | 1.00 | FPR2 (0.64) | FPR2RAB9AMEN1LMNAPOLB | |
| SCHEMBL19549511 | 0.91 | FPR2 (0.66) | FPR2RAB9AMEN1LMNAPOLB | |
| SCHEMBL14906492 | 0.91 | FPR2 (0.66) | FPR2RAB9AMEN1LMNAPOLB | |
| SCHEMBL14902694 | 0.91 | FPR2 (0.53) | FPR2MEN1LMNAPOLBKMT2A | |
| SCHEMBL14902695 | 0.89 | FPR2 (0.53) | FPR2MEN1LMNAPOLBKMT2A | |
| SCHEMBL20484276 | 0.89 | FPR2 (0.67) | FPR2RAB9A | |
| SCHEMBL14906428 | 0.89 | FPR2 (0.67) | FPR2RAB9A | |
| SCHEMBL22175323 | 0.88 | FPR2 (0.74) | FPR2MEN1LMNAPOLBKMT2A | |
| SCHEMBL14906429 | 0.88 | FPR2 (0.74) | FPR2MEN1LMNAPOLBKMT2A | |
| SCHEMBL14902677 | 0.88 | FPR2 (0.74) | FPR2MEN1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3078656-B1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-07-01 | — | — | EP | disclosed |
| EP-2770989-B1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2018-09-05 | — | — | EP | disclosed |