Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28257989 | 0.84 | BUB1 (0.33) | BUB1DDB1CRBN | |
| SCHEMBL27219481 | 0.81 | BUB1 (0.36) | BUB1DDB1CRBN | |
| SCHEMBL26915679 | 0.81 | BUB1 (0.36) | BUB1DDB1CRBN | |
| SCHEMBL17937395 | 0.81 | BUB1 (0.36) | BUB1DDB1CRBN | |
| SCHEMBL25301908 | 0.78 | BUB1 (0.38) | BUB1DDB1CRBN | |
| SCHEMBL350967 | 0.78 | BUB1 (0.38) | BUB1DDB1CRBN | |
| SCHEMBL31456782 | 0.78 | BUB1 (0.38) | BUB1DDB1CRBN | |
| SCHEMBL4792482 | 0.75 | BUB1 (0.34) | BUB1DDB1CRBN | |
| SCHEMBL4745464 | 0.74 | GRIN2B (0.34) | — | |
| SCHEMBL21244820 | 0.72 | BUB1 (0.40) | BUB1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331552-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010036551-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-01 | — | — | WO | disclosed |