Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28535355 | 0.85 | — | — | |
| SCHEMBL2048424 | 0.84 | BUB1 (0.33) | BUB1DDB1CRBN | |
| SCHEMBL26915679 | 0.79 | BUB1 (0.36) | BUB1GAADDB1CRBN | |
| SCHEMBL27219481 | 0.79 | BUB1 (0.36) | BUB1GAADDB1CRBN | |
| SCHEMBL17937395 | 0.79 | BUB1 (0.36) | BUB1GAADDB1CRBN | |
| SCHEMBL25301908 | 0.78 | BUB1 (0.38) | BUB1GAADDB1CRBN | |
| SCHEMBL31456782 | 0.78 | BUB1 (0.38) | BUB1GAADDB1CRBN | |
| SCHEMBL350967 | 0.78 | BUB1 (0.38) | BUB1GAADDB1CRBN | |
| SCHEMBL23858688 | 0.78 | KDM4E (0.33) | GAA | |
| SCHEMBL23858690 | 0.78 | KDM4E (0.33) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-B | Aminoheteroaryl benzamide as kinase inhibitor | 诺华股份有限公司 | 2018-11-27 | — | — | CN | disclosed |