Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 3/20 | 0.42 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.41 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20484562 | 1.00 | OPRM1 (0.43) | OPRM1OPRK1MALT1CAPN1CTSB | |
| SCHEMBL20484560 | 1.00 | OPRM1 (0.43) | OPRM1OPRK1MALT1CAPN1CTSB | |
| SCHEMBL20484549 | 0.89 | MALT1 (0.52) | MALT1 | |
| SCHEMBL20484552 | 0.89 | MALT1 (0.52) | MALT1 | |
| SCHEMBL20484554 | 0.89 | MALT1 (0.52) | MALT1 | |
| SCHEMBL22798205 | 0.89 | MALT1 (0.52) | MALT1 | |
| SCHEMBL20484708 | 0.86 | MALT1 (0.46) | MALT1 | |
| SCHEMBL20484707 | 0.86 | MALT1 (0.46) | MALT1 | |
| SCHEMBL20484569 | 0.86 | MALT1 (0.43) | OPRM1OPRK1MALT1 | |
| SCHEMBL20484567 | 0.86 | MALT1 (0.43) | OPRM1OPRK1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | Cornell University Cornell Center for Technology Enterprise & Commercialization (CCTEC) (US) | 2018-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | MALT1, BCL3, BCL6 | OPRM1 4510/4885OPRK1 4587/4885MALT1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.