Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20485185 | 1.00 | MALT1 (0.43) | MALT1KCNH2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20485181 | 1.00 | MALT1 (0.43) | MALT1KCNH2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20485178 | 0.92 | MALT1 (0.41) | MALT1KCNH2OPRM1OPRK1F2 | |
| SCHEMBL20484723 | 0.92 | MALT1 (0.41) | MALT1KCNH2OPRM1OPRK1F2 | |
| SCHEMBL20485182 | 0.92 | MALT1 (0.41) | MALT1KCNH2OPRM1OPRK1F2 | |
| SCHEMBL20484726 | 0.92 | MALT1 (0.41) | MALT1KCNH2OPRM1OPRK1F2 | |
| SCHEMBL20484728 | 0.92 | MALT1 (0.41) | MALT1KCNH2OPRM1OPRK1F2 | |
| SCHEMBL18619573 | 0.89 | MALT1 (0.53) | MALT1KCNH2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20485174 | 0.88 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2 | |
| SCHEMBL20485176 | 0.88 | OPRM1 (0.49) | OPRM1OPRD1OPRK1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | Cornell University Cornell Center for Technology Enterprise & Commercialization (CCTEC) (US) | 2018-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | MALT1, BCL3, BCL6 | MALT1 1/4885KCNH2 4814/4885CYP3A4 1335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.