⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28674387 | 0.90 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL8048638 | 0.90 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL8041724 | 0.88 | CES2 (0.44) | — | |
| SCHEMBL27617098 | 0.85 | MAPT (0.30) | — | |
| SCHEMBL23254519 | 0.84 | PLG (0.52) | — | |
| SCHEMBL9238948 | 0.80 | GSR (0.35) | — | |
| SCHEMBL14344917 | 0.77 | MAPT (0.44) | — | |
| SCHEMBL28269483 | 0.75 | TP53 (0.35) | — | |
| SCHEMBL14448427 | 0.74 | MAPT (0.42) | — | |
| SCHEMBL3028991 | 0.74 | HTT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116769253-B | Geogrid modified polypropylene engineering plastic and preparation method and application thereof | 山东路德新材料股份有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-117024878-A | Modified polypropylene geogrid raw material and geogrid | 山东路德新材料股份有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116769253-A | Geogrid modified polypropylene engineering plastic and preparation method and application thereof | 山东路德新材料股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116769253-B | Geogrid modified polypropylene engineering plastic and preparation method and application thereof | 山东路德新材料股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117024878-A | Modified polypropylene geogrid raw material and geogrid | 山东路德新材料股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116769253-A | Geogrid modified polypropylene engineering plastic and preparation method and application thereof | 山东路德新材料股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116547287-A | Inhibitors of APOL1 and methods of use thereof | 弗特克斯药品有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-107922407-B | Respiratory syncytial virus inhibitors | 勃林格殷格翰国际有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-111164069-A | N- (3- (2- (4-chlorophenoxy) acetamido) bicyclo [1.1.1] pent-1-yl) -2-cyclobutane-1-carboxamide derivatives and related compounds as ATF4 inhibitors for the treatment of cancer and other diseases | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-106170489-B | New Pyrazolopyrimidine derivative and its purposes as MALT1 inhibitor | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-107922407-A | Respiratory Syncytial Virus(RSV) inhibitor | 美迪维尔公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-104147011-A | Uses of pyridine-diketone serving as PDE4 inhibitor for treating eye diseases | ASTRAZENECA AB | 2014-11-19 | — | — | CN | disclosed |
| CN-102105448-B | Phenoxypyridinylamide derivatives and use thereof in the treatment of PDE4 mediated disease states | ASTRAZENECA AB | 2013-11-13 | — | — | CN | disclosed |
| CN-101636388-B | 637 pyridopyrimidinediones as PDE4 inhibitors | ASTRAZENECA AB | 2013-09-18 | — | — | CN | disclosed |
| CN-101932577-B | Heteroaryl-substituted piperidines | BAYER HEALTHCARE AG | 2013-07-17 | — | — | CN | disclosed |
| CN-102532135-A | Chemical compounds 637: pyridopyrimidinediones as pde4 inhibitors | ASTRAZENECA AB | 2012-07-04 | — | — | CN | disclosed |
| EP-2231575-B1 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL INTERMEDIATES | EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDOE RESZVENYTARSASAG (HU) | 2011-06-22 | — | — | EP | disclosed |
| CN-102105448-A | Phenoxypyridinylamide derivatives and their use in the treatment of PDE4 mediated disease states | ASTRAZENECA AB | 2011-06-22 | — | — | CN | disclosed |
| CN-101932577-A | Heteroaryl-substituted piperidines | BAYER HEALTHCARE AG | 2010-12-29 | — | — | CN | disclosed |
| CN-101636388-A | Compound 637: pyridopyrimidinediones as PDE4 inhibitors | ASTRAZENECA AB | 2010-01-27 | — | — | CN | disclosed |