Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2046507 | 1.00 | TRIM24 (0.38) | TRIM24TRIM33ALDH1A1CRBNMAPT | |
| SCHEMBL2046509 | 1.00 | TRIM24 (0.38) | TRIM24TRIM33ALDH1A1CRBNMAPT | |
| SCHEMBL7533356 | 0.88 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1MAPTPDE4A | |
| SCHEMBL7529781 | 0.88 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1MAPTPDE4A | |
| SCHEMBL112495 | 0.88 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1MAPTPDE4A | |
| SCHEMBL2053850 | 0.88 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1MAPTPDE4A | |
| SCHEMBL18244192 | 0.88 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1MAPTPDE4A | |
| SCHEMBL7530266 | 0.88 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1MAPTPDE4A | |
| SCHEMBL2053848 | 0.88 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1MAPTPDE4A | |
| SCHEMBL7532471 | 0.88 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1MAPTPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173846-B2 | Substituted cyclohexenones | FIRMENICH SA (CH) | 2012-05-08 | — | — | US | disclosed |
| US-8173846-B2 | Substituted cyclohexenones | FIRMENICH SA (CH) | 2012-05-08 | — | — | US | disclosed |
| US-8173846-B2 | Substituted cyclohexenones | FIRMENICH SA (CH) | 2012-05-08 | — | — | US | disclosed |
| EP-2247564-B1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH & CIE (CH) | 2011-06-29 | — | — | EP | disclosed |
| EP-2247564-B1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH & CIE (CH) | 2011-06-29 | — | — | EP | disclosed |
| EP-2247564-A1 | SUBSTITUTED CYCLOHEXENONES | Firmenich S.A. (CH) | 2010-11-10 | — | — | EP | disclosed |
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2010-10-28 | — | — | US | disclosed |
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2010-10-28 | — | — | US | disclosed |
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2010-10-28 | — | — | US | disclosed |
| WO-2009095804-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2009-08-06 | — | — | WO | disclosed |
| WO-2009095804-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2009-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | OXER1, ORC3, OR10J3 | TRIM24 3668/4885TRIM33 2859/4885ALDH1A1 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.