Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529781 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMKNK2 | |
| SCHEMBL18244192 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMKNK2 | |
| SCHEMBL112495 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMKNK2 | |
| SCHEMBL7533356 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMKNK2 | |
| SCHEMBL7532471 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMKNK2 | |
| SCHEMBL7529787 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMKNK2 | |
| SCHEMBL16258755 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMKNK2 | |
| SCHEMBL7530266 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMKNK2 | |
| SCHEMBL2053850 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMKNK2 | |
| SCHEMBL868351 | 1.00 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264594-B1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO PERFUMERY CO LTD (JP) | 2006-11-29 | — | — | EP | claimed |
| US-6759557-B2 | MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-07-06 | — | — | US | claimed |
| US-20030049213-A1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-03-13 | — | — | US | claimed |
| EP-1264594-A2 | Melanin production inhibitors and skincare products containing such inhibitors | Takasago International Corporation (JP) | 2002-12-11 | — | — | EP | claimed |
| EP-0025869-B1 | 3-METHYL-CYCLOHEXADECEN-5-ONE-1, PROCESS FOR ITS PREPARATION, AND ITS USE AS ODORANT | HAARMANN & REIMER GMBH (DE) | 1983-09-28 | — | — | EP | claimed |
| US-20160000691-A1 | Topical Compositions And Methods For Whitening Skin | ELC MAN LLC (US) | 2016-01-07 | — | — | US | disclosed |
| US-8173846-B2 | Substituted cyclohexenones | FIRMENICH SA (CH) | 2012-05-08 | — | — | US | disclosed |
| US-20110171288-A1 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | MOHAMMADI FATEMEH | 2011-07-14 | — | — | US | disclosed |
| EP-2247564-B1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH & CIE (CH) | 2011-06-29 | — | — | EP | disclosed |
| EP-2254546-A2 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | ELC Management LLC (US) | 2010-12-01 | — | — | EP | disclosed |
| EP-2247564-A1 | SUBSTITUTED CYCLOHEXENONES | Firmenich S.A. (CH) | 2010-11-10 | — | — | EP | disclosed |
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2010-10-28 | — | — | US | disclosed |
| WO-2009105294-A2 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | ELC MANAGEMENT LLC (US) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009095804-A1 | SUBSTITUTED CYCLOHEXENONES | FIRMENICH SA (CH) | 2009-08-06 | — | — | WO | disclosed |
| EP-1264594-B1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO PERFUMERY CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-20050271608-A1 | Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives | GUPTA SHYAM K | 2005-12-08 | — | — | US | disclosed |
| US-6759557-B2 | MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-07-06 | — | — | US | disclosed |
| US-20030049213-A1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-03-13 | — | — | US | disclosed |
| EP-1264594-A2 | Melanin production inhibitors and skincare products containing such inhibitors | Takasago International Corporation (JP) | 2002-12-11 | — | — | EP | disclosed |
| EP-0584477-B1 | Use of a cyclopentadecenone as a perfuming ingredient | FIRMENICH & CIE (CH) | 1997-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000691-A1 | Topical Compositions And Methods For Whitening Skin | CUTA, COL14A1, KRT18 | TRIM24 4075/4885TRIM33 3413/4885ALDH1A1 863/4885 |
| US-20100274059-A1 | SUBSTITUTED CYCLOHEXENONES | OXER1, ORC3, OR10J3 | TRIM24 3668/4885TRIM33 2859/4885ALDH1A1 175/4885 |
| US-20030049213-A1 | Melanin production inhibitors and skincare products containing such inhibitors | TYR, AOC3, DOHH | TRIM24 444/4885TRIM33 4685/4885ALDH1A1 322/4885 |
| US-20110171288-A1 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | CUTA, COL14A1, KRT18 | TRIM24 4075/4885TRIM33 3413/4885ALDH1A1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.