Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | SIK1 | P57059 | 1/20 | 0.41 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.41 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488740 | 0.88 | MTNR1A (0.52) | FGFR1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL19911345 | 0.86 | FGFR1 (0.52) | FGFR1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL19911342 | 0.81 | KMT2A (0.48) | FGFR1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL24110390 | 0.79 | KMT2A (0.46) | FGFR1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL24109893 | 0.79 | KMT2A (0.46) | FGFR1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL24110493 | 0.79 | KMT2A (0.46) | FGFR1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL24109956 | 0.79 | FGFR1 (0.49) | FGFR1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL19848126 | 0.78 | KMT2A (0.45) | FGFR1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL24110481 | 0.77 | BRD4 (0.46) | FGFR1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL24110476 | 0.77 | KMT2A (0.45) | FGFR1KMT2AHPGDTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018158365-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-07 | — | — | WO | disclosed |