Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.57 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709439 | 1.00 | SCN3A (0.57) | SCN3ASCN9ADHODHPSMB8ITGB3 | |
| SCHEMBL2709126 | 0.90 | SCN3A (0.70) | SCN3ASCN9ADHODHPSMB8WNT1 | |
| SCHEMBL205890 | 0.90 | SCN3A (0.70) | SCN3ASCN9ADHODHPSMB8WNT1 | |
| SCHEMBL15586493 | 0.88 | SCN3A (0.49) | SCN3ASCN9ADHODHPSMB8ITGB3 | |
| SCHEMBL18849750 | 0.87 | SCN3A (0.56) | SCN3ASCN9ADHODHPSMB8WNT1 | |
| SCHEMBL28651738 | 0.87 | SCN3A (0.56) | SCN3ASCN9ADHODHPSMB8WNT1 | |
| SCHEMBL15692991 | 0.87 | SCN3A (0.48) | SCN3ASCN9ADHODHPSMB8ITGB3 | |
| SCHEMBL10222792 | 0.84 | SCN3A (0.57) | SCN3ASCN9ADHODHPSMB8WNT1 | |
| SCHEMBL18849650 | 0.84 | SCN3A (0.53) | SCN3ASCN9ADHODHPSMB8WNT1 | |
| SCHEMBL18849675 | 0.84 | SCN3A (0.53) | SCN3ASCN9ADHODHPSMB8WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| US-8088368-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2012-01-03 | — | — | US | disclosed |