Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.70 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.70 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 2/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709126 | 1.00 | SCN3A (0.70) | SCN3ASCN9ADHODHIKBKBCHUK | |
| SCHEMBL204893 | 0.90 | SCN3A (0.57) | SCN3ASCN9ADHODHIKBKBCHUK | |
| SCHEMBL2709439 | 0.90 | SCN3A (0.57) | SCN3ASCN9ADHODHIKBKBCHUK | |
| SCHEMBL18849750 | 0.89 | SCN3A (0.56) | SCN3ASCN9ADHODHIKBKBCHUK | |
| SCHEMBL28651738 | 0.89 | SCN3A (0.56) | SCN3ASCN9ADHODHIKBKBCHUK | |
| SCHEMBL15586705 | 0.89 | SCN3A (0.59) | SCN3ASCN9ADHODHIKBKBCHUK | |
| SCHEMBL10222792 | 0.88 | SCN3A (0.57) | SCN3ASCN9ADHODHIKBKBCHUK | |
| SCHEMBL24731039 | 0.86 | SCN3A (0.55) | SCN3ASCN9ADHODHIKBKBCHUK | |
| SCHEMBL18849675 | 0.86 | SCN3A (0.53) | SCN3ASCN9ADHODHIKBKBCHUK | |
| SCHEMBL2693904 | 0.86 | SCN3A (0.55) | SCN3ASCN9ADHODHIKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| US-8088368-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2012-01-03 | — | — | US | disclosed |