⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2049127 | 0.94 | — | — | |
| SCHEMBL10882922 | 0.92 | — | — | |
| SCHEMBL4808304 | 0.92 | — | — | |
| SCHEMBL4810017 | 0.92 | — | — | |
| SCHEMBL4808494 | 0.92 | — | — | |
| SCHEMBL4806856 | 0.92 | — | — | |
| SCHEMBL6361615 | 0.90 | — | — | |
| SCHEMBL7872904 | 0.88 | — | — | |
| SCHEMBL29441744 | 0.87 | — | — | |
| SCHEMBL9420801 | 0.85 | THRB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956131-B2 | Lactam polymer derivatives | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-06-07 | — | — | US | disclosed |
| US-20100171923-A1 | LACTAM POLYMER DERIVATIVES | JOHSNON & JOHNSON VISION CARE, INC. | 2010-07-08 | — | — | US | disclosed |
| EP-2029641-A2 | LACTAM POLYMER DERIVATIVES | ETHICON, INC. (US) | 2009-03-04 | — | — | EP | disclosed |
| US-7473738-B2 | Lactam polymer derivatives | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2009-01-06 | — | — | US | disclosed |
| WO-2008157468-A1 | LACTAM POLYMER DERIVATIVES | ETHICON, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
| US-20070299206-A1 | LACTAM POLYMER DERIVATIVES | ETHICON, INC. | 2007-12-27 | — | — | US | disclosed |
| WO-2007149804-A2 | LACTAM POLYMER DERIVATIVES | ETHICON, INC. (US) | 2007-12-27 | — | — | WO | disclosed |
| US-20070290174-A1 | LACTAM POLYMER DERIVATIVES | JOHNSON & JOHNSON VISION CARE, INC. | 2007-12-20 | — | — | US | disclosed |
| US-20060069235-A1 | Lactam polymer derivatives | JOHNSON & JOHNSON VISION CARE, INC. | 2006-03-30 | — | — | US | disclosed |