SCHEMBL2048950

SCHEMBL2048950

O=C1CCCCC(C(O)CO)O1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 3/20 0.39
LMNA P02545 2/20 0.36
MAPT P10636 1/20 0.36
MANBA O00462 1/20 0.36
THRB P10828 1/20 0.36
HIF1A Q16665 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
CYP1A2 P05177 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12198629 0.95 PRKCA (0.40) PRKCALMNAMAPTMANBATHRB
SCHEMBL12321141 0.95 PRKCA (0.40) PRKCALMNAMAPTMANBATHRB
SCHEMBL8378158 0.87 PRKCA (0.48) PRKCALMNAMAPTMANBATHRB
SCHEMBL8142299 0.87 PRKCA (0.48) PRKCALMNAMAPTMANBATHRB
SCHEMBL8776236 0.87 PRKCA (0.48) PRKCALMNAMAPTMANBATHRB
SCHEMBL23530392 0.85 PRKCA (0.32) PRKCA
SCHEMBL29825928 0.85 PRKCA (0.32) PRKCA
SCHEMBL29826071 0.85 PRKCA (0.32) PRKCA
SCHEMBL23530390 0.85 PRKCA (0.32) PRKCA
SCHEMBL29825846 0.85 PRKCA (0.32) PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114470321-A Tubular nanofiber material and preparation method thereof 深圳先进技术研究院 2022-05-13 CN claimed
CN-111281975-A Preparation method of boron-containing nano-targeted drug 四川瑶天纳米科技有限责任公司 2020-06-16 CN claimed
US-9422234-B2 Prostate specific membrane antigen (PSMA) targeted nanoparticles for therapy of prostate cancer THE JOHNS HOPKINS UNIVERSITY (US) 2016-08-23 US claimed
CN-103622915-B A kind of targeted nano delivery system for cerebral glioma FUDAN UNIVERSITY (CN) 2015-10-07 CN claimed
CN-104606140-A Method for preparing high drug-loading rate nanoparticles for treating liver cancer DENG XIN 2015-05-13 CN claimed
CN-104491848-A Anti-AIDS nano-microsphere DENG XIN 2015-04-08 CN claimed
CN-104398480-A Estrogen-containing nanometer particle and its preparation method RUIKANG HOSPITAL AFFILIATED TO GUANGXI UNIVERSITY OF CHINESE MEDICINE 2015-03-11 CN claimed
CN-104324011-A Anti-cancer nanometer drug microsphere and preparation method thereof RUIKANG HOSPITAL AFFILIATED TO GUANGXI UNIVERSITY OF CHINESE MEDICINE 2015-02-04 CN claimed
CN-104288126-A Preparation method of nanoparticles with high drug loading capacity for treating cancer RUIKANG HOSPITAL AFFILIATED TO GUANGXI UNIVERSITY OF CHINESE MEDICINE 2015-01-21 CN claimed
CN-102188391-B Method for preparing granulocyte-macrophage colony stimulating factor microsphere UNIV SHANGHAI JIAOTONG 2013-09-25 CN claimed
CN-101574394-A Strychnos alkaloid vesicle and preparation method thereof BEIJING INCREASE PHARM CO LTD (CN) 2009-11-11 CN claimed
CN-101574319-A Podophyllotoxin vesicle and preparation method thereof BEIJING INCREASE PHARM CO LTD (CN) 2009-11-11 CN claimed
CN-101549272-A Method of preparing S/O/W of 5-fluorouracil biodegradable polymer microspheres UNIV SHANGHAI JIAOTONG (CN) 2009-10-07 CN claimed
EP-1991161-A2 BIODEGRADABLE PHOSPHOESTER POLYAMINES Tyco Healthcare Group, LP (US) 2008-11-19 EP claimed
CN-101298150-A Wood preservative complex containing chitose metal complex UNIV ZHEJIANG FORESTRY (CN) 2008-11-05 CN claimed
CN-101091714-A Liposome of precursor containing ginsenoside Rh2, and preparation method CHINA UNIV OF PHARMACY (CN) 2007-12-26 CN claimed
WO-2007100574-A2 BIODEGRADABLE PHOSPHOESTER POLYAMINES TYCO HEALTHCARE GROUP LP (US) 2007-09-07 WO claimed
CN-1326525-C 10-hydroxy camptothecin long cyclic liposome and its freeze aried preparation UNIV FUDAN (CN) 2007-07-18 CN claimed
CN-1679575-A 10-hydroxy camptothecine long circulating vesica and its freeze-dried preparation UNIV FUDAN (CN) 2005-10-12 CN claimed
CN-1650864-A 10-hydroxy camptothecin long cyclic liposome and its freeze aried preparation UNIV FUDAN (CN) 2005-08-10 CN claimed