Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 10/20 | 0.72 |
| ▸ | TUBB | P07437 | 10/20 | 0.72 |
| ▸ | TUBA3C | P0DPH7 | 10/20 | 0.72 |
| ▸ | TUBA1B | P68363 | 10/20 | 0.72 |
| ▸ | TUBA4A | P68366 | 10/20 | 0.72 |
| ▸ | TUBB4B | P68371 | 10/20 | 0.72 |
| ▸ | TUBB3 | Q13509 | 10/20 | 0.72 |
| ▸ | TUBB2A | Q13885 | 10/20 | 0.72 |
| ▸ | TUBB8 | Q3ZCM7 | 10/20 | 0.72 |
| ▸ | TUBA3E | Q6PEY2 | 10/20 | 0.72 |
| ▸ | TUBA1A | Q71U36 | 10/20 | 0.72 |
| ▸ | TUBA1C | Q9BQE3 | 10/20 | 0.72 |
| ▸ | TUBB6 | Q9BUF5 | 10/20 | 0.72 |
| ▸ | TUBB2B | Q9BVA1 | 10/20 | 0.72 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16622701 | 0.84 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16611884 | 0.79 | TUBB4A (0.71) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16612065 | 0.76 | TUBB4A (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16612033 | 0.69 | TUBB4A (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16622719 | 0.68 | TUBB4A (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16611823 | 0.67 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL19979462 | 0.67 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2LMNATSHRHSD17B10 | |
| SCHEMBL16611976 | 0.67 | TUBB4A (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16612517 | 0.67 | TUBB4A (0.66) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16612248 | 0.66 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857393-B1 | N-ARYL UNSATURATED FUSED RING TERTIARY AMINE COMPOUND, PREPARATION METHOD THEREOF AND ANTITUMOR APPLICATION THEREOF | INST PHARMACOLOGY & TOXICOLOGY ACADEMY MILITARY MEDICAL SCIENCES PLA CHINA (CN) | 2018-09-12 | — | — | EP | claimed |