Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10826503 | 0.97 | NPSR1 (0.58) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL27955481 | 0.97 | NPSR1 (0.58) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL14390126 | 0.88 | GLO1 (0.72) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL8832385 | 0.88 | NPSR1 (0.54) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL14518032 | 0.88 | NPSR1 (0.54) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL2049259 | 0.88 | NPSR1 (0.54) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL14261596 | 0.88 | GLO1 (0.72) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL13304509 | 0.88 | NPSR1 (0.54) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL10780939 | 0.86 | NPSR1 (0.52) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL1942274 | 0.81 | NPSR1 (0.62) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272964-B | The 6 substitution Ethyl formate class compounds of 1 ((base of 1 substituted-phenyl, 1,2,3 triazole 4) methyl) 4 carbonyl quinoline 3 and its preparation and application | 河南省医药科学研究院 | 2017-11-24 | — | — | CN | claimed |
| CN-105237512-B | The 6 substitution formic acid of 1 ((base of 1 substituted-phenyl, 1,2,3 triazole 4) methyl) 4 carbonyl quinoline 3 or pharmaceutical salts, preparation and application | 河南省医药科学研究院 | 2017-08-18 | — | — | CN | claimed |
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | claimed |
| US-9065900-B2 | Method and system to shield mobile phones and devices to minimize radiation exposure | GREEN SWAN, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-20110157859-A1 | METHOD AND SYSTEM TO SHIELD MOBILE PHONES AND DEVICES TO MINIMIZE RADIATION EXPOSURE | GREEN SWAN, INC. | 2011-06-30 | — | — | US | disclosed |
| WO-2010038165-A1 | IMIDAZO[1,5]NAPHTHYRIDINE COMPOUNDS, THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2009108838-A1 | BRIDGED, BICYCLIC HETEROCYCLIC OR SPIRO BICYCLIC HETEROCYCLIC DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF | WYETH (US) | 2009-09-03 | — | — | WO | disclosed |
| US-7335466-B2 | Silver salt photothermographic dry imaging material, image recording method and image forming method for the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-02-26 | — | — | US | disclosed |
| US-7335466-B2 | Silver salt photothermographic dry imaging material, image recording method and image forming method for the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-02-26 | — | — | US | disclosed |
| US-7267935-B1 | Thermally developable materials stabilized with crown ethers | CARESTREAM HEALTH, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-7267935-B1 | Thermally developable materials stabilized with crown ethers | CARESTREAM HEALTH, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| EP-1682532-B1 | PYRIMIDINES AS INHIBITORS OF PHOSPHOINOSITIDE-3-KINASES (PI3K) | WARNER LAMBERT CO (US) | 2007-06-27 | — | — | EP | disclosed |
| US-7202019-B2 | Photothermographic imaging material | KONICA MINOLTA HOLDINGS, INC. (JP) | 2007-04-10 | — | — | US | disclosed |
| US-7202019-B2 | Photothermographic imaging material | KONICA MINOLTA HOLDINGS, INC. (JP) | 2007-04-10 | — | — | US | disclosed |
| WO-2007014925-A1 | MACROCYLIC INHIBITORS OF HEPATITIS C VIRUS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2007-02-08 | — | — | WO | disclosed |
| US-7163782-B2 | Photothermographic imaging material | KONICA MINOLTA HOLDINGS, INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7163782-B2 | Photothermographic imaging material | KONICA MINOLTA HOLDINGS, INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | disclosed |
| US-4600781-A | 2-formyl-2-halomalonates and compound derived therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1986-07-15 | — | — | US | disclosed |