Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008977 | 1.00 | LTA4H (0.85) | LTA4HKCNH2 | |
| SCHEMBL1888282 | 1.00 | LTA4H (0.85) | LTA4HKCNH2 | |
| SCHEMBL1898474 | 0.92 | LTA4H (1.00) | LTA4HKCNH2 | |
| SCHEMBL29897047 | 0.92 | LTA4H (1.00) | LTA4HKCNH2 | |
| SCHEMBL1888398 | 0.92 | LTA4H (1.00) | LTA4HKCNH2 | |
| SCHEMBL1007663 | 0.92 | LTA4H (1.00) | LTA4HKCNH2 | |
| SCHEMBL1887903 | 0.90 | LTA4H (0.85) | LTA4HKCNH2 | |
| SCHEMBL15282370 | 0.90 | LTA4H (0.85) | LTA4HKCNH2 | |
| SCHEMBL1884362 | 0.90 | LTA4H (0.85) | LTA4HKCNH2 | |
| SCHEMBL12590544 | 0.89 | LTA4H (0.77) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336125-A1 | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase | Janssen Pharmaceutica N.V. (BE) | 2011-06-22 | — | — | EP | disclosed |