Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115105 | 0.90 | GPR119 (0.53) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL19385731 | 0.86 | MAPT (0.54) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL13261277 | 0.85 | GPR119 (0.59) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL14453584 | 0.85 | GPR119 (0.55) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL31142873 | 0.84 | GPR119 (0.69) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL3922455 | 0.84 | GPR119 (0.69) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL3923112 | 0.84 | GPR119 (0.54) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL4422111 | 0.84 | GPR119 (0.54) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL19582522 | 0.83 | MAPT (0.51) | GPR119MAPTLMNAALDH1A1PDK2 | |
| SCHEMBL29417615 | 0.83 | MAPT (0.51) | GPR119MAPTLMNAALDH1A1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018163077-A1 | INDANYL COMPOUNDS AS VOLTAGE GATED SODIUM CHANNEL MODULATORS | LUPIN LIMITED (IN) | 2018-09-13 | — | — | WO | disclosed |