Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3730926 | 0.91 | MAPT (0.61) | MAPTALDH1A1LMNANPSR1GAA | |
| SCHEMBL30301697 | 0.91 | MAPT (0.61) | MAPTALDH1A1LMNANPSR1GAA | |
| SCHEMBL30301712 | 0.87 | MAPT (0.65) | MAPTALDH1A1LMNANPSR1GAA | |
| SCHEMBL6629173 | 0.87 | MAPT (0.65) | MAPTALDH1A1LMNANPSR1GAA | |
| SCHEMBL957198 | 0.86 | MAPT (0.61) | MAPTALDH1A1LMNANPSR1HTT | |
| SCHEMBL4443971 | 0.85 | MAPT (0.59) | MAPTALDH1A1LMNANPSR1HTT | |
| SCHEMBL16935225 | 0.84 | MAPT (0.58) | MAPTALDH1A1LMNAGAAMAPK1 | |
| SCHEMBL953126 | 0.84 | LMNA (0.61) | MAPTALDH1A1LMNANPSR1ENPP2 | |
| SCHEMBL15801197 | 0.84 | MAPT (0.58) | MAPTALDH1A1LMNANPSR1GAA | |
| SCHEMBL19385731 | 0.82 | MAPT (0.54) | MAPTALDH1A1LMNAENPP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018163077-A1 | INDANYL COMPOUNDS AS VOLTAGE GATED SODIUM CHANNEL MODULATORS | LUPIN LIMITED (IN) | 2018-09-13 | — | — | WO | disclosed |