Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.42 |
| ▸ | XBP1 | P17861 | 4/20 | 0.42 |
| ▸ | MPI | P34949 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629326 | 1.00 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2ANPSR1 | |
| SCHEMBL2049724 | 1.00 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2ANPSR1 | |
| SCHEMBL9900251 | 0.90 | MAPT (0.50) | MAPTKDM4EALDH1A1KMT2ANPSR1 | |
| SCHEMBL9900252 | 0.90 | MAPT (0.50) | MAPTKDM4EALDH1A1KMT2ANPSR1 | |
| SCHEMBL12329007 | 0.88 | KDM4E (0.49) | MAPTKDM4EALDH1A1KMT2ANPSR1 | |
| SCHEMBL213778 | 0.85 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2ANPSR1 | |
| SCHEMBL13656515 | 0.84 | TDP1 (0.45) | MAPTKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL212829 | 0.81 | MAPT (0.53) | MAPTKDM4EALDH1A1KMT2ANPSR1 | |
| SCHEMBL13969947 | 0.81 | MAPT (0.53) | MAPTKDM4EALDH1A1KMT2ANPSR1 | |
| SCHEMBL6024585 | 0.81 | RECQL (0.47) | MAPTKDM4EALDH1A1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | claimed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | claimed |
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |