Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 3/20 | 0.39 |
| ▸ | MPI | P34949 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900251 | 1.00 | MAPT (0.50) | MAPTKDM4EALDH1A1KMT2ACES2 | |
| SCHEMBL12629326 | 0.90 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2AKAT6A | |
| SCHEMBL2049725 | 0.90 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2AKAT6A | |
| SCHEMBL2049724 | 0.90 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2AKAT6A | |
| SCHEMBL12329007 | 0.85 | KDM4E (0.49) | MAPTKDM4EALDH1A1KMT2ACES2 | |
| SCHEMBL9899975 | 0.82 | KDM4E (0.49) | MAPTKDM4EALDH1A1KMT2ACES2 | |
| SCHEMBL9899979 | 0.82 | KDM4E (0.49) | MAPTKDM4EALDH1A1KMT2ACES2 | |
| SCHEMBL12629321 | 0.81 | CES2 (0.43) | MAPTKDM4EALDH1A1KMT2ACES2 | |
| SCHEMBL213778 | 0.79 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2AMAPK1 | |
| SCHEMBL6024583 | 0.78 | RECQL (0.47) | MAPTKDM4EALDH1A1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | claimed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | claimed |
| EP-2649102-B1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORP (JP) | 2014-11-26 | — | — | EP | disclosed |
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |