Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245002 | 1.00 | HCAR2 (0.59) | HCAR2NFE2L2KEAP1ALDH1A1MAPT | |
| SCHEMBL31190394 | 0.92 | HCAR2 (0.50) | HCAR2NFE2L2KEAP1ALDH1A1MAPT | |
| SCHEMBL1088218 | 0.91 | HCAR2 (0.54) | HCAR2NFE2L2KEAP1ALDH1A1MAPT | |
| SCHEMBL1088172 | 0.91 | HCAR2 (0.54) | HCAR2NFE2L2KEAP1ALDH1A1MAPT | |
| SCHEMBL1088175 | 0.91 | HCAR2 (0.54) | HCAR2NFE2L2KEAP1ALDH1A1MAPT | |
| SCHEMBL10712879 | 0.90 | HCAR2 (0.52) | HCAR2NFE2L2KEAP1EPHX1CA12 | |
| SCHEMBL10712880 | 0.90 | HCAR2 (0.52) | HCAR2NFE2L2KEAP1EPHX1CA12 | |
| SCHEMBL9246773 | 0.90 | HCAR2 (0.52) | HCAR2NFE2L2KEAP1EPHX1CA12 | |
| SCHEMBL9241943 | 0.90 | HCAR2 (0.52) | HCAR2NFE2L2KEAP1EPHX1CA12 | |
| SCHEMBL2884283 | 0.88 | ATM (0.39) | HCAR2NFE2L2KEAP1ABCB1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180265527-A1 | Acyl Germanium Photoinitiators And Process For The Preparation Thereof | IVOCLAR VIVADENT AG (LI) | 2018-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180265527-A1 | Acyl Germanium Photoinitiators And Process For The Preparation Thereof | AGPAT5, AGPAT2, GLRA2 | HCAR2 1714/4885NFE2L2 767/4885KEAP1 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.