Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10712880 | 1.00 | HCAR2 (0.52) | HCAR2KEAP1NFE2L2EPHX1NAAA | |
| SCHEMBL10712879 | 1.00 | HCAR2 (0.52) | HCAR2KEAP1NFE2L2EPHX1NAAA | |
| SCHEMBL9241943 | 1.00 | HCAR2 (0.52) | HCAR2KEAP1NFE2L2EPHX1NAAA | |
| SCHEMBL1088218 | 0.98 | HCAR2 (0.54) | HCAR2KEAP1NFE2L2EPHX1NAAA | |
| SCHEMBL1088172 | 0.98 | HCAR2 (0.54) | HCAR2KEAP1NFE2L2EPHX1NAAA | |
| SCHEMBL1088175 | 0.98 | HCAR2 (0.54) | HCAR2KEAP1NFE2L2EPHX1NAAA | |
| Ethane SCHEMBL28092403 | 0.90 | EPHX1 (0.47) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 | |
| SCHEMBL20497366 | 0.90 | HCAR2 (0.59) | HCAR2KEAP1NFE2L2EPHX1HTT | |
| SCHEMBL9245002 | 0.90 | HCAR2 (0.59) | HCAR2KEAP1NFE2L2EPHX1HTT | |
| SCHEMBL8101682 | 0.89 | EPHX1 (0.48) | EPHX1NAAAHTTSMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534236-B1 | Moulding compositions of polymethylmethacrylate with high heat resistance | BASF AG (DE) | 1995-12-06 | — | — | EP | disclosed |
| EP-0534236-A2 | Moulding compositions of polymethylmethacrylate with high heat resistance | BASF Aktiengesellschaft (DE) | 1993-03-31 | — | — | EP | disclosed |