SCHEMBL2049798

SCHEMBL2049798

C1=CCC(c2ccccc2)N=C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.36
MAOB P27338 8/20 0.35
MAOA P21397 7/20 0.35
KDM1A O60341 5/20 0.35
CYP2C19 P33261 4/20 0.35
CYP2B6 P20813 3/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2D6 P10635 3/20 0.35
CYP2C9 P11712 2/20 0.35
LMNA P02545 2/20 0.35
KCNH2 Q12809 2/20 0.35
CYP3A4 P08684 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2A6 P11509 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30880193 0.80 KDM1A (0.39) KDM1ASLC6A2HTR2CSLC6A3NOS2
SCHEMBL14781166 0.76 HTR2A (0.32) MAOBKDM1AHTR2CMAPK1
SCHEMBL7262663 0.73 ALDH1A1 (0.37) CYP1A2LMNAHSD17B10BLMALPL
SCHEMBL20172556 0.71 SLC6A4 (0.39) KDM1ACYP2A6SLC6A2HTR2CSLC6A3
SCHEMBL10969488 0.71 CYP2C19 (0.33) TAAR1CYP2C19
SCHEMBL9834266 0.71 KDM1A (0.46) KDM1ASLC6A2SLC6A3BLMALOX12
SCHEMBL10969469 0.71 CYP2C19 (0.33) TAAR1CYP2C19
SCHEMBL9062578 0.70 ALDH1A1 (0.41) CYP2C19CYP1A2CYP2D6CYP2C9LMNA
SCHEMBL10997701 0.69
SCHEMBL7220032 0.68 TAAR1 (0.37) TAAR1MAOBMAOAKDM1ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240384142-A1 (METH)ACRYLATE-BASED TOUGHENED ADHESIVES HENKEL AG & CO. KGAA (DE) 2024-11-21 US claimed
WO-2023147115-A1 (METH)ACRYLATE-BASED TOUGHENED ADHESIVES HENKEL AG & CO. KGAA (DE) 2023-08-03 WO claimed
EP-2912131-B1 ADHESIVE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2018-06-06 EP claimed
US-9657203-B2 Adhesive compositions Henkel IP & Holding GmbH (DE) 2017-05-23 US claimed
US-9574118-B2 Adhesive compositions Henkel IP & Holding GmbH (DE) 2017-02-21 US claimed
CN-103958628-B Adhesive composition Henkel IP & Holding GmbH (DE) 2016-02-17 CN claimed
EP-2912131-A1 ADHESIVE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2015-09-02 EP claimed
US-20150225626-A1 ADHESIVE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2015-08-13 US claimed
CN-104781358-A Adhesive compositions Henkel US IP LLC 2015-07-15 CN claimed
US-20140235758-A1 ADHESIVE COMPOSITIONS Henkel US IP LLC (US) 2014-08-21 US claimed
CN-103958628-A Adhesive composition HENKEL CORP 2014-07-30 CN claimed
WO-2014066315-A1 ADHESIVE COMPOSITIONS Henkel US IP LLC (US) 2014-05-01 WO claimed
US-8231758-B2 Acrylic adhesives HENKEL CORPORATION (US) 2012-07-31 US claimed
CN-101688100-B Acrylic adhesives HENKEL CORP 2012-04-18 CN claimed
US-20100101724-A1 ACRYLIC ADHESIVES HENKEL CORPORATION (US) 2010-04-29 US claimed
CN-101688100-A Acrylic adhesive HENKEL CORP 2010-03-31 CN claimed
US-20100065210-A1 FLOWABLE NON-SAGGING ADHESIVE COMPOSITIONS HENKEL CORPORATION (US) 2010-03-18 US claimed
WO-2009009009-A2 ACRYLIC ADHESIVES HENKEL CORPORATION (US) 2009-01-15 WO claimed
WO-2008057414-A1 FLOWABLE, NON-SAGGING ADHESIVE COMPOSITIONS HENKEL CORPORATION (US) 2008-05-15 WO claimed
US-20230265315-A1 TWO-PART, SILANE MODIFIED POLYMER/FREE RADICALLY CURABLE ADHESIVE SYSTEMS Henkel AG & Holding GmbH (DE) 2023-08-24 US disclosed
EP-4176017-A1 TWO-PART, SILANE MODIFIED POLYMER/FREE RADICALLY CURABLE ADHESIVE SYSTEMS Henkel AG & Co. KGaA (DE) 2023-05-10 EP disclosed
WO-2022006486-A1 TWO-PART, SILANE MODIFIED POLYMER/FREE RADICALLY CURABLE ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2022-01-06 WO disclosed
US-9636339-B2 Phenyl-dihydropyridine derivatives as aldosterone synthase inhibitors HOFFMAN-LA ROCHE INC. (US) 2017-05-02 US disclosed
US-9636338-B2 Phenyl-dihydropyridine derivatives as inhibitors of aldosterone synthase HOFFMANN-LA ROCHE INC. (US) 2017-05-02 US disclosed
CN-105593212-A New phenyl-dihydropyridine derivatives as aldosterone synthase inhibitors HOFFMANN LA ROCHE 2016-05-18 CN disclosed
CN-105531263-A Phenyl-dihydropyridine derivatives as inhibitors of aldosterone synthase HOFFMANN LA ROCHE 2016-04-27 CN disclosed
EP-1691936-B1 CORROSION PROTECTIVE METHACRYLATE ADHESIVES FOR GALVANIZED STEEL AND OTHER METALS Henkel IP & Holding GmbH (DE) 2015-09-02 EP disclosed
US-8304024-B2 Corrosion protective methacrylate adhesives for galvanized steel and other metals HENKEL CORPORATION (US) 2012-11-06 US disclosed
US-8231758-B2 Acrylic adhesives HENKEL CORPORATION (US) 2012-07-31 US disclosed
CN-101688100-B Acrylic adhesives HENKEL CORP 2012-04-18 CN disclosed
US-7956143-B1 Toughened two-part adhesive compositions demonstrating improved impact and/or peel strengths when cured HENKEL CORPORATION (US) 2011-06-07 US disclosed
US-20100101724-A1 ACRYLIC ADHESIVES HENKEL CORPORATION (US) 2010-04-29 US disclosed
CN-101688100-A Acrylic adhesive HENKEL CORP 2010-03-31 CN disclosed
US-20090286089-A1 ACRYLIC-BASED ADHESIVES FOR POLYVINYLIDENE SURFACES HENKEL CORPORATION (US) 2009-11-19 US disclosed
EP-1691936-A4 CORROSION PROTECTIVE METHACRYLATE ADHESIVES FOR GALVANIZED STEEL AND OTHER METALS HENKEL CORP (US) 2009-08-05 EP disclosed
WO-2009009009-A2 ACRYLIC ADHESIVES HENKEL CORPORATION (US) 2009-01-15 WO disclosed
WO-2007145879-A2 ACRYLIC-BASED ADHESIVES FOR THE SURFACES WITH A FLUOROCARBON-CONTAINING COATING HENKEL CORPORATION (US) 2007-12-21 WO disclosed
US-20060194069-A1 Corroxion Protective Methacrylate Adhesives for Galvanized Steel and Other Metals HENKEL CORPORATION 2006-08-31 US disclosed
EP-1691936-A2 CORROSION PROTECTIVE METHACRYLATE ADHESIVES FOR GALVANIZED STEEL AND OTHER METALS Henkel Corporation (US) 2006-08-23 EP disclosed
US-7060327-B2 Corrosion protective methacrylate adhesives for galvanized steel and other metals HENKEL CORPORATION (US) 2006-06-13 US disclosed
US-20060011293-A1 Corrosion protective methacrylate adhesives for galvanized steel and other metals HENKEL CORPORATION 2006-01-19 US disclosed
WO-2005049879-A2 CORROSION PROTECTIVE METHACRYLATE ADHESIVES FOR GALVANIZED STEEL AND OTHER METALS HENKEL CORPORATION (US) 2005-06-02 WO disclosed
WO-1996033972-A1 METHODS FOR SYNTHESIZING DIVERSE COLLECTIONS OF PYRIDINES, PYRIMIDINES, 1,4-DIHYDRO DERIVATIVES THEREOF, AND PIPERIDINE DERIVATIVES GLAXO GROUP LIMITED (GB) 1996-10-31 WO disclosed
CN-1090284-A The anti-inflammatory of dual-use function and immunosuppressor CYTOMED INC (US) 1994-08-03 CN disclosed
US-5246705-A Thermoplastic or crosslinked elastomer CYGNUS THERAPEUTIC SYSTEM (US) 1993-09-21 US disclosed
EP-0315018-A3 FLUOROMETHOXYPHENYL-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DRUGS BAYER AG (DE) 1990-07-18 EP disclosed
EP-0315019-A3 FLUOROMETHOXYPHENYL-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DRUGS BAYER AG (DE) 1990-07-18 EP disclosed
EP-0315018-A2 Fluoromethoxyphenyl-dihydropyridines, process for their preparation and their use in drugs BAYER AG (DE) 1989-05-10 EP disclosed
EP-0315018-A2 Fluoromethoxyphenyl-dihydropyridines, process for their preparation and their use in drugs BAYER AG (DE) 1989-05-10 EP disclosed
EP-0315019-A2 Fluoromethoxyphenyl-dihydropyridines, process for their preparation and their use in drugs BAYER AG (DE) 1989-05-10 EP disclosed
EP-0315019-A2 Fluoromethoxyphenyl-dihydropyridines, process for their preparation and their use in drugs BAYER AG (DE) 1989-05-10 EP disclosed