SCHEMBL2050106

SCHEMBL2050106

C=CCC1(CC=CC)C(=O)NC(=O)N(c2ccccc2)C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.43
PGR P06401 2/20 0.42
ALDH1A1 P00352 5/20 0.34
MAPT P10636 3/20 0.34
KDM4E B2RXH2 3/20 0.34
HSD17B10 Q99714 3/20 0.34
LMNA P02545 2/20 0.34
CASP1 P29466 1/20 0.34
GAA P10253 1/20 0.33
RECQL P46063 1/20 0.33
GRK5 P34947 1/20 0.33
TYRO3 Q06418 1/20 0.33
DYRK1B Q9Y463 1/20 0.33
GABRA1 P14867 3/20 0.33
GABRG2 P18507 3/20 0.33
GABRB3 P28472 3/20 0.33
GABRB2 P47870 2/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
NR4A1 P22736 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2050104 1.00 ELANE (0.43) ELANEPGRALDH1A1MAPTKDM4E
SCHEMBL2047107 0.91 PGR (0.48) ELANEPGRALDH1A1MAPTKDM4E
SCHEMBL2047367 0.85 ELANE (0.50) ELANEPGRALDH1A1
SCHEMBL2047369 0.85 ELANE (0.50) ELANEPGRALDH1A1
SCHEMBL2045521 0.82 PGR (0.34) ELANEPGRALDH1A1MAPTLMNA
SCHEMBL2045522 0.82 PGR (0.34) ELANEPGRALDH1A1MAPTLMNA
SCHEMBL2045783 0.80 CYP2C19 (0.47) ELANEALDH1A1MAPTKDM4EHSD17B10
SCHEMBL2045781 0.80 CYP2C19 (0.47) ELANEALDH1A1MAPTKDM4EHSD17B10
SCHEMBL2045934 0.80 KDM4E (0.43) ELANEPGRALDH1A1KDM4ELMNA
SCHEMBL2045937 0.80 KDM4E (0.43) ELANEPGRALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964691-B2 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-21 US disclosed
WO-2009038031-A1 BLOCK COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
WO-2009038006-A1 RANDOM COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
US-20080214755-A1 OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
US-20080214754-A1 DIENE POLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed