Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.48 |
| ▸ | SQLE | Q14534 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31632707 | 1.00 | KMT2A (0.54) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL11548663 | 0.98 | KMT2A (0.52) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL28149947 | 0.98 | KMT2A (0.57) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL20414120 | 0.98 | KMT2A (0.52) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL11548660 | 0.98 | KMT2A (0.52) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL6820912 | 0.96 | KMT2A (0.55) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL6820914 | 0.96 | KMT2A (0.55) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL11449012 | 0.84 | KMT2A (0.56) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL10989158 | 0.84 | KMT2A (0.48) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL7285585 | 0.84 | KMT2A (0.56) | KMT2AMEN1CYP3A4ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765035-A1 | TOPICAL THERAPY FOR THE TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN) AND CERVICAL CANCER USING NANOPARTICLES OF TAXANES | DFB Soria, LLC (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019178024-A1 | TOPICAL THERAPY FOR THE TREATMENT OF CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN) AND CERVICAL CANCER USING NANOPARTICLES OF TAXANES | DFB SORIA, LLC (US) | 2019-09-19 | — | — | WO | disclosed |
| CN-108778244-A | DELIVERY OF DRUG NANOPARTICLES AND METHODS OF USE THEREOF | DFB索里亚有限责任公司 | 2018-11-09 | — | — | CN | disclosed |
| WO-2018170210-A1 | TOPICAL THERAPY FOR THE TREATMENT OF VULVAR INTRAEPITHELIAL NEOPLASIA (VIN) AND GENITAL WARTS USING NANOPARTICLES OF TAXANES | DFB SORIA, LLC (US) | 2018-09-20 | — | — | WO | disclosed |