Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.50 |
| ▸ | SQLE | Q14534 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820914 | 1.00 | KMT2A (0.55) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL28149947 | 0.98 | KMT2A (0.57) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL20414120 | 0.98 | KMT2A (0.52) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11548660 | 0.98 | KMT2A (0.52) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11548663 | 0.98 | KMT2A (0.52) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL31632707 | 0.96 | KMT2A (0.54) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL20501916 | 0.96 | KMT2A (0.54) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL25993302 | 0.88 | KMT2A (0.39) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11485915 | 0.83 | KMT2A (0.58) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10987811 | 0.83 | KMT2A (0.52) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311261-A4 | MEDICAMENTS FOR CHEMOTHERAPEUTIC TREATMENT OF DISEASE | PHOTOGEN INC (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1311261-A1 | MEDICAMENTS FOR CHEMOTHERAPEUTIC TREATMENT OF DISEASE | Photogen, Inc. (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002005812-A1 | MEDICAMENTS FOR CHEMOTHERAPEUTIC TREATMENT OF DISEASE | PHOTOGEN, INC. (US) | 2002-01-24 | — | — | WO | disclosed |