Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.57 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652090 | 0.90 | FAAH (0.81) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL12350003 | 0.90 | FAAH (0.81) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL342410 | 0.90 | FAAH (0.81) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL3994160 | 0.90 | FAAH (0.81) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL17203936 | 0.90 | FAAH (0.81) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL15649498 | 0.90 | FAAH (0.81) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL12349998 | 0.90 | FAAH (0.81) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL8512461 | 0.90 | FAAH (0.81) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL15649884 | 0.90 | FAAH (0.81) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL3643202 | 0.90 | FAAH (0.81) | FAAHMEN1MAPK1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |